29/08/2025
Prostate cancer diagnosis isn’t one-size-fits-all—today’s urologists use a sophisticated, layered approach with a variety of new and traditional tests 🧬🩺. In my latest article, I break down 17 key diagnostic tools, showing you what each test measures, how accurate it is, and where it fits in your care pathway. Here’s a quick overview of what you’ll discover:
Blood Tests
Learn about the classic PSA, the more specific Free-to-Total PSA Ratio, advanced risk assessments like the Prostate Health Index (PHI) and 4Kscore, and the modern IsoPSA test. These blood tests help determine if further investigation is needed or can reduce unnecessary worry and avoid invasive procedures.
Physical and Imaging Exams
Find out how the Digital Re**al Exam (DRE) checks for hidden lumps, and explore how multiparametric MRI and high-resolution micro-ultrasound provide high-detail, non-invasive inner views of the prostate. PSMA PET scans come into play when mapping the spread of cancer or spotting recurrence.
Urine and Tissue-Based Tests
Discover innovative urine-based assays like PCA3, SelectMDx, and ExoDx, which offer non-invasive ways to assess cancer risk. When tissue confirmation is needed, get the facts about systematic TRUS biopsies, modern transperineal approaches, and high-precision MRI–ultrasound fusion biopsies that target exactly where cancer might be hiding
Genomic and Molecular Panels
Rounding out the journey, see how ConfirmMDx and genomic panels (Oncotype DX, Prolaris, Decipher) dive into genetic and molecular details, offering personalized insights that help decide between monitoring and treatment.
✨ Every step aims to balance accuracy and comfort, reducing unnecessary biopsies and overtreatment while not missing aggressive cancer. Want to be fully informed and prepared to discuss your options?
Read the complete guide now!
👉 Explore all 17 tests in detail hereashwinsridharurology
Explore prostate cancer diagnostic tests—from PSA to imaging—with expert insight from Dr. Ashwin Sridhar.