07/07/2025
🫀 A new pre-clinical study has uncovered how oestrogen may help protect women’s hearts – especially when blood pressure is high.
A team at has discovered in mice that oestrogen boosts a natural protein (ANXA1) that helps shield the heart from damage. Without it, the heart becomes more vulnerable – especially in females.
Although early days and lots more research is needed, especially in humans (this study was in mice), this breakthrough could lead to new, female-focused treatments for high blood pressure and heart disease – a long-overlooked area in medicine.
“There’s an urgent need to uncover the distinct mechanisms driving hypertension and its cardiovascular complications in females - an underexplored population. Closing this knowledge gap is essential for developing more effective, sex-specific treatments,” Dr Qin, co-lead author of the study said.
PMID: 40619476
📌 A step forward in understanding why heart disease affects women differently – and what we can do about it.
The ANXA1 protein can have anti inflammatory protective effects, in this case on heart health in relation to high blood pressure in mice.
🥗Big segue, but a reminder to also eat anti inflammatory foods where possible, based around the Mediterranean style diet , which is full of anti inflammatory heart healthy food like nuts, seeds, veggies, fruit, legumes and olive oil.
🥦🥕🍆🧅🧄🌶️🍒🫛🍎🍊🥑🫘
