
22/09/2023
Glutamine + gut health
Glutamine isn't going anywhere. It's being sold as the elixir for gut health. But what does the evidence say?
When it comes general gut health, there little evidence to suggest it helps for people without illness. Even the evidence in those that are unwell is pretty weak still for many diseases or conditions. For example:
☑️ Post-infectious IBS research is fairly limited, what it does show is that there may be a benefit. However, one study may not have had the minimal amount of participants needed. More evidence is needed.
☑️ IBS alongside a low FODMAP diet. There is some evidence but again the study has some things to consider. For example the placebo group (without glutamine) had more women, those with unspecified IBS subtype and constipation. These are just some factors that may have influenced the effectiveness of a low FODMAP diet in the first place. Again more evidence is needed!
☑️ For many other diseases such as inflammatory bowel disease there is insufficient evidence.
My verdict on glutamine supplements?
For whatever reason you want to take glutamine, there is probably a more evidence based strategy out there for you. We know that glutamine is abundant in the body, and in basically any protein rich food. Therefore you probably do not need more.
If you're wanting to try it anyway, then that's fine too. Glutamine supplements have a low risk of side effects, but it's with checking that supplements are suitable for you before taking. For doses, studies sometimes use 15g per day split into 3x 5g doses. You could try this for 8-12 weeks and review if it's helped you or not. If no difference, discontinue 😌
If you're suffering with a disease or a health condition, you may be depleting glutamine in the body more rapidly that others. But always check with your dietitian or doctor to see if supplements are your safest and best bet. There may be alternatives you're better off investing in.
P.S. This post only covers a small area of research on glutamine, mainly on the gut. It does not cover all uses ❤️