21/11/2025
Before drinking:
* NAC (N-acetylcysteine) 600-1200mg about 30 minutes before - this supports glutathione production, which helps your liver process acetaldehyde (the toxic alcohol metabolite that causes much of hangover misery)
* B-complex vitamin - alcohol depletes B vitamins rapidly, especially B1, B6, and B12
* Electrolytes - start hydrated with minerals like magnesium, potassium, and sodium
* Eat a substantial meal with healthy fats and protein to slow alcohol absorption
During drinking:
* Alternate each alcoholic drink with water containing electrolytes
* Stick to clearer spirits if possible - darker alcohols have more congeners (fermentation byproducts) that worsen hangovers
* Avoid sugary mixers which can exacerbate blood sugar crashes
Before bed:
* More water with electrolytes
* Milk thistle (silymarin) 150-300mg - supports liver detoxification
* Another dose of NAC if you didn’t take it earlier
* Magnesium glycinate 200-400mg - helps with sleep quality and muscle relaxation
Women-specific considerations:
* Women generally have lower levels of alcohol dehydrogenase (the enzyme that breaks down alcohol), so the same amount affects us more
* Hormonal fluctuations DO matter…you’ll likely feel effects more during the luteal phase (post-ovulation)
* Consider lower alcohol intake overall due to these metabolic differences
The key is being proactive rather than reactive….prevention works far better than trying to fix things the next morning.