17/02/2026
The Silent Epidemic 🌍🩺
We are pleased to share that our latest systematic review, "Chronic kidney disease in hypertensive patients: the urgent need for targeted interventions in Arab countries," has been published in Frontiers in Nephrology.
With Chronic Kidney Disease ( ) projected to be the 5th leading cause of years of life lost globally by 2040, understanding its relationship with hypertension (HTN) in our region is critical.
🔬 Following PRISMA 2020 guidelines and a PROSPERO-registered protocol, we conducted a rigorous systematic review of studies across the Arab region, including , the , , , , and , to evaluate the prevalence and management gaps of CKD among hypertensive populations.
📊 A Call for Early Detection!! Our synthesis of the evidence reveals a concerning landscape of undiagnosed disease and missed opportunities for prevention:
• The "Silent" Burden: A staggering proportion of CKD cases remain unrecognised; studies in the UAE and Jordan found that 31% to 38.8% of patients had undiagnosed CKD.
• The association is undeniable; in Iraq, over 75% of CKD patients were found to be hypertensive, yet blood pressure control remains suboptimal, with fewer than 40% of patients achieving target levels in some cohorts.
• We identified a critical gap in screening quality; while physicians check eGFR, albuminuria testing is frequently overlooked. In one Jordanian study, 92% of high-risk participants had not undergone an albumin test, leading to significant underdiagnosis.
• In Saudi Arabia, studies indicated that nearly 47% of hypertensive patients had CKD, with a significant portion already in stages 3–5.
💡 Why This Matters for the Region: The Arab region is facing a rapid epidemiological transition with rising rates of and . Our findings underscore that we cannot rely on eGFR alone.
To build resilient health systems in Arab countries, we must integrate combined eGFR and albuminuria testing into primary care routine screening for all hypertensive patients.
Strengthening primary care capacity to detect CKD early is the only way to prevent progression to end-stage renal disease.
A special thank you to co-authors Fakhria Alrashdi, Zeenah Atwan, Celine Tabche, Nasrin Al Zadjali, Samiya AL-Khaldi, Hamed Al-Qanubi and Prof. Salman Rawaf for this important collaboration and the School of Public Health at Imperial College London.
📖 Read the full open-access paper here: https://doi.org/10.3389/fneph.2026.1735217
BackgroundChronic kidney disease (CKD) is expected to be the 5th leading cause of years of life lost by 2040. Recently, it emerged as a significant cause of ...