MRC Laboratory of Medical Sciences

MRC Laboratory of Medical Sciences The LMS is a vibrant research environment in which scientists and clinicians collaborate to advance the application of biology to medicine.

What is Team Science? πŸ‘¨β€πŸ”¬πŸ‘©β€πŸ”¬πŸ§‘β€πŸ”¬At the LMS we are committed to a transdisciplinary team science approach πŸ§¬πŸ§«πŸ”¬By bringing t...
05/11/2025

What is Team Science? πŸ‘¨β€πŸ”¬πŸ‘©β€πŸ”¬πŸ§‘β€πŸ”¬

At the LMS we are committed to a transdisciplinary team science approach πŸ§¬πŸ§«πŸ”¬

By bringing together expertise from across many disciplines we can tackle big problems.

The Team Science programme at the LMS began more than two years ago. Staff were invited to workshops discussing the intersection of LMS expertise and facilities, and what projects could be tackled. These gave rise to a collection of some 500+ individual questions which were curated, categorised and prioritised. Subsequent workshops focused on narrowing down these questions into big challenges that the LMS is uniquely placed to answer with the right people and the right approach.

Watch this space for our big announcement soon!

Happy Halloween! The skull is an image of the DNA of stem cells from a mouse embryo taken by one of our postdocs, Gosia ...
31/10/2025

Happy Halloween!

The skull is an image of the DNA of stem cells from a mouse embryo taken by one of our postdocs, Gosia Borkowska.

The eyes of the skull are formed by the nucleus of two cells, while the surrounding β€˜bones’ are chromosomes that are preparing for cell division.

The cells have been fixed (chemically preserved) in paraformaldehyde and then stained with a dye called DAPI, which can enter both fixed and live cells, to bind the DNA so we can visualise the genetic material.

07/10/2025

New work from and his lab has uncovered previously unknown links between our genes and heart shape πŸ«€πŸ©·

This was achieved using a technique called 3-dimensional genomic wide analysis study (3D GWAS). 3D GWAS allows for a comparison between 3D heart structure and genomics. By performing 3D GWAS on over 40,000 UK Biobank participants the study was able to find new genetic loci that influence heart structure.

The video was created using heart MRIs and demonstrates how the heart contracts. This model was used in the analysis of the participants hearts.

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