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18/02/2026

Tamoxifen Side Effects Can Be Tough 💜

If you're taking tamoxifen, side effects can sometimes feel hard to balance against the long-term benefits.

A lot of people tell us the hardest part is managing symptoms for years, while still wanting to stay on treatment 🙏

Here are 7 common side effects and what can help to manage them:

🔹 Hot flashes and night sweats
🔹 Vaginal dryness
🔹 Fatigue
🔹 Mood changes
🔹 Weight gain or fluid retention
🔹 Joint pain or bone pain
🔹 Nausea and vomiting

Did you know you can use the OWise to track your side effects? Tracking can help you spot patterns, communicate clearly with your care team and get the support you need 💜➡️ https://owi.se/dl

17/02/2026

Tamoxifen Tuesday: Managing changes to periods🌺

Irregular periods or missed periods can happen because tamoxifen blocks estrogen receptors in reproductive tissues💊🚫

A missed period doesn’t automatically mean menopause❌

If your period stops it may return after finishing tamoxifen for some people⏰

But if you’re on tamoxifen for years (sometimes up to 10 years) periods may not return because you may enter menopause naturally over that time💁‍♀️

Track any changes (dates, flow, spotting) so your team can support you and rule out other causes📊👩‍⚕️ You can do this on the FREE OWise app📱
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Save this for later and head over to our blog “How to Deal with Tamoxifen Side Effects” for more💜✨

⚠️Links in the comments section⚠️

16/02/2026

Metastatic Mondays: Using blood tests to change treatment before scans show progression🩸

‼️ This post is about metastatic HR+ breast cancer in people taking hormone therapy (camizestrant vs standard endocrine therapy) alongside a CDK4/6 inhibitor‼️

In the SERENA-6 trial, researchers looked at whether monitoring circulating tumour DNA (ctDNA) — tumour DNA found in the blood — could help guide treatment decisions🧬

They specifically monitored for an emerging ESR1 mutation, which can be a sign that the cancer is starting to develop resistance to the current hormone therapy👩‍⚕️

If an ESR1 mutation appeared in the blood, people switched their hormone therapy earlier, while continuing on the same CDK4/6 inhibitor💊🔄

Why this matters: This supports a future approach where treatment changes can be guided by a blood test, meaning someone may be able to switch therapy before scans show progression🙏

⚠️Important note: Camizestrant is still investigational and isn’t standard care yet⚠️

Please share to help spread awareness and follow for more posts🙏💜

14/02/2026

HER2+ breast cancer series part 2 ➡️ Managing Common Side Effects of Early
HER2+ Breast Cancer Treatment 💜

Side effects can be tough & you deserve support for them 🙌

Here are common side effects during early HER2+ treatment, plus practical ways to manage them:

🔹 Heart problems
🔹 Breathlessness
🔹 Nausea and vomiting
🔹 Diarrhoea
🔹 Constipation
🔹 Fatigue
🔹 Low white blood cell/neutropenia
🔹 Low red blood cells/anaemia
🔹 Hair loss

Learn more about early HER2+ breast cancer here 💜 https://owise.uk/her2/

13/02/2026

Breast Cancer Breakdown: Breast Cancer Subtypes💜

Molecular subtypes are based on specific characteristics of cancer cells🧫⬇️

🔸Hormone receptor-positive (HR+) - cancer growth influenced by estrogen and progesterone hormones

🔸HER2-positive (HER2+) - HER2 protein is expressed in high amounts leading to abnormal cell division and growth

🔸HER2-low - low amounts of the HER2 protein (new evidence suggests up to 55% of all breast cancers may be HER2-low)

🔸Triple negative breast cancer (TNBC) - cancer growth not influenced by hormones or HER2

Save this for later and head over to our blog “Understanding Your Breast Cancer Diagnosis: A Guide” for more💾📖

🔗 https://owise.uk/understanding-breast-cancer-diagnosis/

12/02/2026

Making breast cancer more manageable💜

Here’s how you can get the most from your appointments⬇️✨

1️⃣ Download the free OWise app📱

2️⃣ Access a list of suggested personalised questions❓

3️⃣Tick them off throughout your appointment✅

Try the OWise app today🫶🔗owi.se/dl

11/02/2026

Early HER2+ breast cancer series part 1 ➡️ What you need to know about early HER2+ breast cancer 💜

HER2+ breast cancer cells have high levels (it is over expressed) of the HER2 protein on the cell surface, leading to abnormal cell division and growth 📈

Swipe through to learn:

🔹 How HER2 is measured
🔹 Treatments for early HER2+ breast cancer - monoclonal antibodies, antibody-drug conjugates and kinase inhibitors
🔹 Common side effects of early HER2+ treatments
🔹 Advancements in early HER2+ treatments

Want somewhere to store all your information in one place? On the OWise app you can add your treatments, appointments, side effects, questions and more 💜🔗 https://owi.se/dl

10/02/2026

Tamoxifen Tuesday: Managing fluid retention💦💊

Here’s some tips⬇️✨

🔸Reduce salty or processed foods (salt can make you retain more fluid)🧂

🔸Try elevating your feet/ankles when resting (prop them up on a pillow)🦶

🔸Avoid long periods of standing or sitting - gentle movement can help circulation🚶‍♀️

🔸Wear loose fitting clothing if swelling makes things feel tight or uncomfortable👚

🔸Elevate your head slightly at night if you wake with puffy eyes🛌

🔸Ask your care team if compression socks may help🧦

🔸Speak to your care team if swelling is painful, severe, or getting worse👩‍⚕️

Save this for later and follow for more💾💜

Read more about about managing tamoxifen side effects on our blog “How to Deal with Tamoxifen Side Effects”📖

🔗 https://owise.uk/tamoxifen-side-effects/

09/02/2026

Metastatic Mondays: Updates on Datroway for metastatic TNBC💜

The TROPION-Breast02 trial tested Datroway (deruxtecan / Dato-DXd) as a first-line treatment for TNBC in patients who aren’t eligible for immunotherapy🥼🧑‍⚕️ It was compared against standard chemotherapy💊

The results found⬇️

🔸Datroway delayed disease progression (PFS): 10.8 months vs 5.6 months on chemo⏰

🔸Datroway improved overall survival (OS): 23.7 months vs 18.7 months on chemo📈

Datroway could become a new chemo-alternative for some people with metastatic TNBC, once approved💊

Share this post to spread awareness and stay tuned for our next post💜🙏
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Read more from us here👉 https://owise.uk/blogs/

08/02/2026

Written by Carly Moosah🙏

Listen to your body. You know what feels good for you💜
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Head over to the OWise website to read our blogs✨👉 https://owise.uk/blogs/

07/02/2026

Chemoseries 4️⃣ - Staying healthy during chemotherapy 💜

Chemotherapy impacts everyone differently, sometimes patients can lead a somewhat normal life while others can find everyday life more challenging 🙏

Side effects can vary for each patient, but there are some important things everyone on chemotherapy should be aware of.

Let’s take a look at:

🔹 why chemotherapy can increase infection risk
🔹 what neutropenia is and when it’s most likely to happen
🔹 simple steps to reduce your risk of infection
🔹 signs of anaemia and how it’s managed
🔹 food choices that may help support iron levels
🔹 s*x, contraception and safety during chemotherapy

Read more about navigating chemotherapy treatment safely here 🔗 https://owise.uk/navigating-chemotherapy-breast-cancer/

06/02/2026

Breast cancer is often described by where the cancer starts (ducts vs lobules) and whether it has invaded nearby breast tissue (in situ/non-invasive vs invasive 💜

In situ (non-invasive) means the cells are still contained in their original site and haven’t spread into surrounding breast tissue:

🔹 DCIS - abnormal cells in the milk ducts (often called stage 0). It isn’t invasive, but it can become invasive over time if untreated.

🔹 LCIS - it isn’t usually considered breast cancer. It is benign (non-harmful) but it may increase the risk of developing breast cancer in the future

Invasive (also known as no special type or NST) means the cells have spread into nearby breast tissue:

🔹 IDC - the most common invasive type (starts in ducts) and accounts for around 80% of invasive breast cancer cases

🔹 ILC starts in lobules and accounts for around 10% of invasive breast cancer cases.

Want to learn more about breast cancer types? Head over to the article 👉 https://owise.uk/understanding-breast-cancer-diagnosis/

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