07/08/2020
* Can nutrition with mushrooms increase neurological reserve?*
A research team, based at the Faculty of Medicine of the University of Coimbra (FMUC) and the Centre for Neuroscience and Cell Biology (CNC) in Coimbra, Portugal, has found that adult mice feeding Coriolus mushroom versicolor increased the complexity of new neurons (nerve cells) formed in the hippocampus, an area of the brain linked to emotions and memory.
Also contributed to this study by Dr. Jorge Valero, affiliated with the University of the Basque Country (UPV / EHU), Leioa, Spain and the Basque Foundation Ikerbasca for Science, Bilbao, Bizkaia, Spain.
Researchers discovered that feeding mice with Coriolus versicolor resulted in a significant increase in the length, volume and arborization (fine branching) of dendrites (extensions of finger-shaped neurons that allow them to communicate with each other) of the newly generated neurons in the hippocampus.
They also discovered that this increased ‘dendritic complexity’ was accompanied by an increase in the levels of the protein β-catenin within these neurons. β-catenin plays a major role in neurogenesis (the development of new neurons) through a process known as Wnt/β-catenin signalling.
Ferreiro, et al. Coriolus versicolor biomass increases dendritic arborization of neurons newly generated in the toothed twist of the hippocampus of mice. Oncotarget, 2018, Vol. 9. (No 68) pp. 32929-32942.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152478/
Thus, the positive effect of Coriolus versicolor on the dendritic complexity of newly generated hippocampus neurons may be influenced, at least in part, by rising catenin levels and improving Wnt / b-signage catenina.
Researchers concluded that the Coriolus versicolor supplement has a previously unexplored neurogenic potential and could represent a preventative strategy for neurological conditions involving cognitive impairment.
* More studies need to be carried out.
Mycology Research Labs supplied Coriolus versicolor for the study. (https://www.mycologyresearch.com/)
Reishi, Maitake, Shiitake, Cordyceps sinensis, Poria cocos, Hericium erinaceus, Pleurotus ostreatus, Agaricus blazei, Chaga, Auricularia,HPV-LSIL Coriolus