15/11/2019
Pain killers & Ovulation | I’m a 28 / 29 day girl, regular as ever. But this cycle was different. I had my bleed on day 23 with 1 day spotting before and the most horrendous PMT for 3 days before hand.
Completely taken a back by this, I reflected on the last month.
- wisdom tooth removal on day 2 of last cycle
- 2 weeks, full dose ibuprofen for pain following complications.
Never usually taking any pain killers, I was a little naive to think I would be completely unaffected. Ibuprofen is part of a family of medication called non-steroidal anti-inflammatory pain killers (NSAIDs). Other drugs in this category include common period pain/endo painkillers such as diclofenac, naproxen and etoricoxib.
But these drugs could prevent ovulation in as many as 75% of fertile women who take them during their follicular phase, according to a study conducted in 2015. As well as inhibiting ovulation, progesterone levels were lower in the women who took NSAIDs, which researcher Salman said could prevent implantation of a fertilised egg if a woman were to ovulate.
My early cycle and spotting premenstrually are all indicators of low progesterone born from luteal phase deficiency or in this case a lack of ovulation due to high dose Ibuprofen use in my follicular phase.
This is a gentle reminder out there to women who are actively TTC or regulate their cycles that taking these “common” pain killers may be having a knock on effect on your delicate hormonal balance and therefore, fertility.
The Pharmaceutical Journal, 27 June/4 July 2015, Vol 294, No 7868/9, online | DOI: 10.1211/PJ.2015.20068779