NCA Research & Innovation

NCA Research & Innovation Research & Innovation is an integrated service at Northern Care Alliance NHS Foundation Trust.

Research helps to improve public health and patient care – it’s the way we improve treatments in the NHS and make a real difference to people’s lives. Our Research and Innovation department is recognised nationally and internationally as a leading centre for clinical trials and other studies, with more than 500 projects carried out here each year. Research links closely with clinical care and teaching to ensure patients and their wellbeing are at the heart of everything we do. Our research includes experimental medicine, which looks at the causes of disease, how certain treatments work and whether they are safe, as well as large scale clinical trials which test the effectiveness of new drugs and treatments. It means patients have access to some of the most cutting edge treatments and thousands of them volunteer to take part in our studies each year.. We work closely with the Universities of Manchester and Salford as well as other NHS organisations and also collaborate nationally and internationally with other experts in our fields.

Older people admitted to hospital after a fall are also at higher risk of developing acute kidney problems, research sho...
27/08/2025

Older people admitted to hospital after a fall are also at higher risk of developing acute kidney problems, research shows.

Acute kidney injury (AKI) is one of the most common complications during hospitalisation and is associated with significant worsening of clinical outcomes including inpatient mortality, extended hospital stay, and development of chronic kidney disease (CKD).

Now colleagues from Northern Care Alliance NHS Foundation Trust, working with researchers from the universities of Manchester and Southampton, have carried out the first comprehensive evaluation of AKI risk in older trauma patients.

The work has been published in the journal PLOS One. Co-lead author Advanced Clinical Practitioner Elizabeth Finnimore said: "We know AKI has been estimated to develop in up to half of severely injured patients and is a leading cause of organ failure and consequently death so it’s crucial that trauma units are aware of the risks and also of the different risks for older people.”

Our very helpful, responsive and pleasant research star of the month at Oldham Care Organisation is Farhan Karim from th...
26/08/2025

Our very helpful, responsive and pleasant research star of the month at Oldham Care Organisation is Farhan Karim from the clinical trials pharmacy team. He's been a huge help with a heart failure study. The research delivery team say they couldn’t have achieved the successful randomization without his, and the wider pharmacy team’s, efficient contribution processing the study prescription on a very time-pressured day.

Peter Elcock is a real survivor. After coming through a terrifying bout of covid that saw him in a coma and relying on a...
23/08/2025

Peter Elcock is a real survivor. After coming through a terrifying bout of covid that saw him in a coma and relying on a ventilator for weeks, he’s been hit by several other health setbacks – but the 59-year-old says he’s a lucky man enjoying his family and working life and looking to the future.

That includes taking part in a research study into the long covid that still affects him day to day, as well as sharing experiences and advice with other covid survivors in a support group.

“The NHS has kept me alive,” he says. “That’s why I want to help. My life isn’t just about me – people have tried so much to help and support me, I’ve seen the best of the NHS."

Thank you to Peter and all the other research participants who have shared their stories on our website - we are inspired by them every day.

Very proud of Rumbi Gore & Danyal Mohammed from our community research team at Northern Care Alliance NHS Foundation Tru...
22/08/2025

Very proud of Rumbi Gore & Danyal Mohammed from our community research team at Northern Care Alliance NHS Foundation Trust , who've both been shortlisted for National BAME Health and Care Awards CA awards, Rumbi for Future Leader - Next Gen category & Dany for Outstanding Social & Community Care Award. Fingers crossed for 25 September!

Planning your bank holiday weekend? If you're heading over to  festival at the Trafford Centre on 23, 24 and 25 August, ...
21/08/2025

Planning your bank holiday weekend? If you're heading over to festival at the Trafford Centre on 23, 24 and 25 August, make sure you look out for our community research team, who will be having a stall. They will be offering people of Pakistani and Bangladeshi heritage the opportunity to take part in the Genes and Health study, the world’s largest community-based study of genetics and health in British Bangladeshis and British Pakistanis.

Research Star of the Month and physiotherapist Alice McEvoy is Principal Investigator for an important research project ...
19/08/2025

Research Star of the Month and physiotherapist Alice McEvoy is Principal Investigator for an important research project for children and young people with cerebral palsy. Colleagues at Bury Care Organisation say she works tirelessly to make sure the team are meeting the study requirements and supports the team with training. Alice is highly motivated to ensure that children eligible have the opportunity to participate - families who have been recruited into the study have been really excited about the clinical results they are seeing.

Brilliant news -we're thrilled that our Northern Care Alliance NHS Foundation Trust colleagues consultant nephrologist D...
18/08/2025

Brilliant news -we're thrilled that our Northern Care Alliance NHS Foundation Trust colleagues consultant nephrologist Dr Tina Chrysochou, consultant neurosurgeon Miss Tina Karabatsou and clinical academic neurosurgeon Mr Kanna Gnanalingham have all been appointed MAHSC Honorary Clinical Chairs.
The awards recognise their major contributions to their clinical specialities, including excellence in research & education. Huge congratulations to them all!

15/08/2025

Research participant Val Biggs is a powerhouse of positivity despite being diagnosed with the rare muscle-wasting condition inclusion body myositis (IBM) in 2022.
The lack of effective treatments makes research even more important and Val, from North Yorkshire, said that as soon as she received her diagnosis, she was clear she wanted to take part in any relevant studies.

Scientists have discovered a series of biological signals which can predict how chronic kidney disease is likely to prog...
14/08/2025

Scientists have discovered a series of biological signals which can predict how chronic kidney disease is likely to progress.
Published in the American Journal of Nephrology, the researchers show that higher levels of Kidney Injury Molecule-1 (KIM-1), a special marker of kidney damage in the blood and urine, are associated with higher risks of mortality and kidney failure, never before have the two been measured together.
The research follows hot on the heels of their paper published in the Journal of the American Society of Nephrology last month, which measured 21 markers in blood and urine that reflect key processes driving kidney disease, inflammation, and heart disease.
Lead author Dr Thomas McDonnell from Northern Care Alliance NHS Foundation Trust said: “The progression of chronic kidney disease is highly variable between people, so it’s difficult to predict which patients will progress to kidney failure or worse.
“But our work raises the prospect of the development of simple blood or urine tests that could better predict the degree of risk - invaluable information for doctors and patients."

Brilliant   from our neurological intensive care unit and it is wonderful to see it recognised in the Health Service Jou...
13/08/2025

Brilliant from our neurological intensive care unit and it is wonderful to see it recognised in the Health Service Journal awards shortlist.

🏆 We are thrilled to be shortlisted for a prestigious Health Service Journal 2025 Award in the Acute Sector Innovation of the Year category! 🧠✨

The team has been recognised for their pioneering use of reduced array electroencephalogram (EEG) and instant messaging in the treatment of seizures within the Neurological Intensive Care Unit.

This year's awards attracted more than 1,250 entries from across the health sector, with only 245 projects and individuals making it through to the final shortlist.

Winners will be announced at the awards ceremony in November 2025.

A huge congratulations to the team on this outstanding achievement!🌟

https://www.northerncarealliance.nhs.uk/news/nca-news/salford-team-shortlisted-prestigious-healthcare-award

Huge thanks to Rochdale Borough Council Deputy Mayor Cllr Faisal Rana who  recently took part in the Genes & Health stud...
12/08/2025

Huge thanks to Rochdale Borough Council Deputy Mayor Cllr Faisal Rana who recently took part in the Genes & Health study. Cllr Rana is also the assistant cabinet member for public health - Genes & Health is the world’s largest community-based study of genetics and health in British Bangladeshis and British Pakistanis and aims to improve health in people from these communities across the UK and globally.

Here's Danyal from our community research team at today's Bury Mela, promoting  the Genes & Health study,  the world’s l...
09/08/2025

Here's Danyal from our community research team at today's Bury Mela, promoting the Genes & Health study, the world’s largest community-based study of genetics and health in British Bangladeshis and British Pakistanis. It aims to improve health in people from these communities across the UK and globally.

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Our Story

Research helps to improve public health and patient care – it’s the way we improve treatments in the NHS and make a real difference to people’s lives. The Research and Innovation Department is a leading centre for clinical trials and other studies, with more than 500 projects carried out at the Northern Care Alliance’s five hospitals - Salford Royal, the Royal Oldham, Fairfield, Rochdale Infirmary and North Manchester General - each year. Research links closely with clinical care and teaching to ensure patients and their wellbeing are at the heart of everything we do. Our research includes experimental medicine, which looks at the causes of disease, how certain treatments work and whether they are safe, as well as large scale clinical trials which test the effectiveness of new drugs and treatments. It means patients have access to some of the most cutting edge treatments and thousands of them volunteer to take part in our studies each year. The Department also hosts Citizen Scientist , an innovative scheme which gives local people a way to find about and get involved in health research. We work closely with the Universities of Manchester and Salford as well as other NHS organisations and also collaborate nationally and internationally with other experts in our fields.