27/07/2025
If you are in the thick of peri-menopause or have started HRT but are still struggling with symptoms then the DUTCH Complete test could provide you with valuable information. The DUTCH Complete test is the smarter way to manage HRT and peri-menopause.
Hormone changes can be chaotic and blood tests only offer a snapshot of levels that fail to capture the full picture. The DUTCH Complete test uses metabolites in urine samples to gain a detailed, functional insight into what’s going on with your hormones.
Hormones don’t decline in a straight line. In peri-menopause, it’s common for oestrogen levels to spike and crash unpredictably, while progesterone quietly declines in the background. Blood tests can miss these fluctuations entirely. This explains why some women feel anxious, wired but tired or emotionally all over the place, even when their results are technically considered within range. The DUTCH Complete test picks up on these patterns.
The DUTCH test tracks hormone patterns across the day. It gives information on levels of progesterone, oestrogen and testosterone as well as giving information on how well your body is clearing them. This is particularly helpful with HRT use as it helps to identify whether you body is metabolising hormones efficiently or pushing them down pathways that might trigger symptoms like weight gain, breast tenderness or anxiety. For anyone concerned about long-term risks, such as oestrogen-sensitive cancers or fibroids, this detail is incredibly useful. It allows us to intervene early, support detoxification, and make HRT more targeted and effective.
It also assesses your adrenal function by looking at cortisol patterns throughout the day. If you’re waking at 3 am, struggling to switch off or feeling totally depleted, this is often where the answer lies. High or low cortisol can directly impact how you respond to HRT or other treatments, so understanding this is essential.
Cortisol is your body’s primary stress hormone and it plays a central role in hormonal balance. When cortisol is too high because of chronic stress, overwork or anxiety or too low due to adrenal burnout from long-term stress exposure, it can interfere with the way oestrogen and progesterone are used and processed in the body.
For example, high cortisol can suppress progesterone production, which is already declining in peri-menopause. This can worsen symptoms like anxiety, poor sleep, irritability and heavy periods. It also makes the oestrogen to progesterone ratio more unbalanced, amplifying oestrogen dominance symptoms.
Cortisol affects liver detoxification and this is important for breaking down and clearing hormones. It can disrupt liver enzyme activity and deplete nutrients needed for phase 2 detoxification. This is the stage that excretes broken-down hormones. This leads to hormone metabolites recirculating and causing symptoms and imbalances.
The DUTCH Complete also includes markers linked to nutrient status, antioxidant capacity and neurotransmitter activity. This allows us to spot signs of low B vitamins, sluggish detoxification and impaired dopamine and serotonin pathways. Issues with these can contribute to mood swings, fatigue, brain fog, cravings and anxiety.
For women navigating peri-menopause or adjusting to HRT, these insights make a real difference. They allow us to create a personalised plan that addresses your unique biochemistry.
If you’re feeling unheard or are unsure whether your HRT is working for you, or maybe you simply want a clearer picture of what your hormones are doing, the DUTCH Complete test could be the missing piece. I offer one-to-one support and interpretation alongside this test, helping you make sense of your results and build a personalised plan that actually works.
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