
23/06/2025
From 1 July 2025, routine cervical screening intervals will be extended from 3 to 5 years for participants aged 25-49 who test negative after attending cervical screening on or after this date.
The NHS Cervical Screening Programme saves thousands of lives every year by checking for high-risk Human Papilloma Virus (hrHPV) which causes almost all cervical cancers.
In England, women and people with a cervix are currently invited every 3 years between the ages of 25-49 and every 5 years if aged 50-64 years.
In December 2019, HPV primary screening was fully implemented in England. This is a more sensitive and accurate test than the previous ‘smear’ test, which only looked for cervical cell
changes.
HPV testing is the best way to find out at an early stage who is at higher risk of developing the cervical cell changes that over time could potentially lead to cervical cancer if
left untreated. This enables us to offer a more personalised approach to cervical cancer prevention based on an individual’s risk.
Studies have shown that if a person tests negative for hrHPV they are extremely unlikely to go on to develop cervical cancer within the next 10 years. A study1 in England, published by King’s College London, showed that 5-year screening intervals are as safe as 3-year intervals; the same number of cancers will be prevented and less frequent cervical screening tests are needed.
The UK National Screening Committee (UKNSC) reviewed all the robust scientific evidence and recommended a change to a 5-year screening interval for participants aged 25-49 years who test negative for hrHPV at their routine screen. The Department of Health and Social Care (DHSC) has accepted this recommendation.
Next test due dates will not be changed; individuals will be invited at the interval in which they were advised of at the time of their last test.
There will be no change to the clinical pathway for those testing positive for HPV. Where there are no cell changes, they will be invited for screening again in 1 year. If cell changes
are found alongside a positive HPV test, they will be referred directly to a hospital clinic for a colposcopy to check the cervix more closely. An individual will only move onto a 5 year
screening interval after this when they meet the clinical criteria.