26/01/2026
Prescription drugs and your microbiome.
A retrospective study found 167 prescription drugs affect the microbiome in your gut with 78 altering your gut microbiome in ways that persist for years—even after you stop taking them.
Not just antibiotics. Beta-blockers. Benzodiazepines. PPIs. Antidepressants.
Your gut microbiome controls your immune system, mental health, nutrient absorption, inflammation, energy, and mood. Damage it, and you damage everything.
Were you told this when they prescribed the drug? Why not?
Was the narrative more like: "take the drug, manage the symptom, ignore the collateral damage".
But the collateral damage is real. Years after you stop taking the drug, the damage persists.
Here's what you can do:
Don't stop your medication without talking to your doctor. But do ask about the research. Ask about long-term effects on your gut and strategies to protect your microbiome while on the drug.
Work with a herbalist or functional medicine practitioner who understands how to support your gut while on medication.
Focus on fermented foods, fiber, and plant diversity.
Your body is a system. Damage one part, and the whole system suffers.