Gowing Life

27/09/2024

Shilajit, a natural substance often used in traditional Indian medicine, is gaining popularity for its reported health benefits. Formed over centuries in the mountains, it contains powerful antioxidants such as fulvic acid, DBPs, and DCPs, which may help protect against oxidative stress and support cellular health.

While some studies suggest it could help with testosterone levels, bone density, and resistance to fatigue, the evidence is still limited. Many of these studies have potential conflicts of interest due receiving funding from shilajit distributors. It’s also important to remember that shilajit’s composition can vary widely, so any benefits may not apply to all products unless a standardised formulation is used. Always ensure the product is purified to avoid harmful contaminants.

If you’re considering shilajit, consulting with a healthcare professional is essential to ensure it’s appropriate for you.



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Shilajit is a natural compound that has been used in traditional Indian medicine for millennia, and is touted as having…

23/09/2024

Is a little alcohol really better for your health than none at all? A recent meta-analysis challenges this widely held belief. Examining 107 studies with over 4.8 million participants, researchers found that, when former drinkers were excluded and studies focused on younger, healthier populations, the health benefits of low-level alcohol consumption largely disappeared.

In fact, the slight reduction in mortality risk for moderate drinkers (compared to non-drinkers) was not statistically significant. This suggests that the perceived health benefits of moderate drinking may be due to confounding factors, such as non-drinkers having pre-existing health issues.

While earlier studies showed a "J-shaped" curve—indicating that light drinking reduced mortality risk compared to non-drinkers—the curve flattened when more rigorous studies were considered.

The conclusion? The idea that small amounts of alcohol are healthier may be an illusion, driven by biases and incomplete data. Always consider potential conflicts of interest in studies—this one, for instance, received support from a temperance organisation.



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Everyday our team of researchers in Oxford are inundated with scientific, and medical research articles that have the potential to improve health, wellbeing, and longevity.

20/09/2024

Methylene blue, a dye long used in laboratories and medicine, may also offer promise in the fight against ageing. Known for its powerful antioxidant and anti-inflammatory properties, it protects cells from oxidative stress, a key contributor to the ageing process. Methylene blue shows potential in preserving mitochondrial health, which is crucial as mitochondrial decline is believed to be a significant driver of ageing.

Research in animals suggests that methylene blue might improve brain function, reduce inflammation, and even extend lifespan, particularly in neurological diseases. There’s also some intriguing evidence that methylene blue could help combat skin ageing by promoting wound healing and skin hydration. However, most of these findings are still early-stage, and evidence in humans is currently limited.

While methylene blue is being studied for Alzheimer’s and skin ageing, it’s essential to be cautious of claims surrounding methylene blue products, as they are often misleading when it comes to the strength of the evidence. More research is needed before we can fully understand its anti-ageing potential.

For now, methylene blue is a fascinating compound with possibilities, but it is not yet a proven solution for slowing down ageing in healthy individuals.



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Methylene blue is a blue dye that is used in laboratories all around the world, and is also used in…

18/09/2024

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16/09/2024

Tattoos are more popular than ever, but are they safe? Recent research suggests there may be a link between tattoos and an increased risk of malignant lymphoma, a type of cancer affecting white blood cells. A study found that people with tattoos were 21% more likely to be diagnosed with lymphoma compared to those without. The risk was higher shortly after receiving a tattoo and also appeared to spike after laser tattoo removal.

While this sounds concerning, it’s important to keep perspective. A 21% increase in risk still represents a small number overall. Lymphoma remains relatively rare, and many other factors like lifestyle and smoking may also play a role. This study is observational, meaning it can’t prove that tattoos directly cause cancer. More research is needed to understand the full implications, but these findings certainly warrant attention for anyone considering tattoos or tattoo removal.

To the article: https://www.gowinglife.com/longevity-briefs-do-tattoos-increase-cancer-risk/

Everyday our team of researchers in Oxford are inundated with scientific, and medical research articles that have the potential to improve health, wellbeing, and longevity.

13/09/2024

New research suggests that the ageing process may occur in "waves" at different life stages, particularly around the ages of 44 and 60. This discovery was made by scientists who tracked 108 participants aged 25 to 75 using a "multi-omics" approach—a comprehensive method that examines various molecular changes across the body.

🔍 What did they find? The researchers noticed that significant shifts in molecules affecting cardiovascular, muscle, skin, and immune function occurred during these two key periods of life. The first wave, at around 44, also included changes related to lipid and alcohol metabolism. The second wave, around 60, brought more molecular changes tied to immune and kidney function.

💡 While the causes of these changes aren’t entirely clear, the findings align with past studies that show ageing is far from a steady process. It happens in bursts, with certain molecular systems facing more disruption at specific points in life. This could be due to biological factors, external stressors, or other life changes, and more research is needed to fully understand these patterns.

🌿 The good news? Though ageing might not be entirely avoidable, a growing body of evidence indicates that adopting healthy habits—such as regular exercise, balanced nutrition, and stress management—can help delay the onset of age-related diseases and disabilities, even when started later in life.

Stay curious, and remember, the science of ageing is continuously evolving, providing us with new insights on how to live healthier, longer lives.



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Everyday our team of researchers in Oxford are inundated with scientific, and medical research articles that have the potential to improve health, wellbeing, and longevity.

11/09/2024

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09/09/2024

New research sheds light on the role of diet in potentially lowering the risk of dementia, even for older adults who already have metabolic or cardiovascular diseases. The study followed over 80,000 dementia-free adults aged 60 and above for more than 12 years, investigating the effects of an anti-inflammatory diet on brain health.

Key Findings:

Those with cardiometabolic diseases who consumed anti-inflammatory diets were less likely to develop dementia and showed better brain health on MRI scans compared to those on pro-inflammatory diets.
Even among individuals without prior disease, a pro-inflammatory diet was linked to a 21% increase in dementia risk, while those with cardiometabolic diseases saw a 44% increase when following the same diet.
While diet may not be the only factor, and causality can't be fully confirmed, these findings suggest that adopting an anti-inflammatory diet rich in fibre, polyphenols, and low in saturated fats may support brain health in later life.

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Everyday our team of researchers in Oxford are inundated with scientific, and medical research articles that have the potential to improve health, wellbeing, and longevity.

08/09/2024

A fascinating new study explores the possibility of transferring regenerative genes from species like starfish and hydra to less regenerative organisms, like fruit flies. Researchers introduced highly regenerative species-specific genes (HRJDs) into flies to see if it would enhance their lifespan or healing abilities.

The findings? Some surprises. When these genes were active during the fly’s development, the flies actually lived shorter lives and had less regeneration in their wings. However, when HRJDs were activated only after the flies had matured into adults, lifespan extension was observed—particularly due to improved gut function.

The research reveals that the interplay of regenerative genes is complex and influenced by many factors. The hope is that by understanding how these genes work, we may uncover insights into the biology of ageing, though applying this knowledge to humans is still a long way off.

This study highlights the unpredictable nature of gene-environment interactions and the challenge of applying regenerative biology across species.

To the article: https://www.gowinglife.com/longevity-briefs-transferring-regenerative-genes-from-one-species-to-another/

Everyday our team of researchers in Oxford are inundated with scientific, and medical research articles that have the potential to improve health, wellbeing, and longevity.

06/09/2024

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04/09/2024

August brought us a fascinating array of discoveries that span the natural world, history, and even quantum physics. Here are some of the highlights:

Weaverbirds’ Ingenious Nests: These birds don’t just build; they design. By weaving grass and creating false entrances, they outsmart predators.

Firework Jellyfish: The rare Halitrephes maasi, known as the firework jellyfish, showcases nature's deep-sea light show.

Coal-Seam Fires: These underground fires can burn for millennia, as seen in Centralia, Pennsylvania, where a fire has raged since the 1960s.

Flanderization in Fiction: Characters can evolve, sometimes excessively. The Simpsons' Ned Flanders is a prime example of how traits can be exaggerated to the point of dominating a character.

Quantum Entanglement in the Brain: Research suggests that quantum effects might play a role in consciousness, possibly via the brain's myelin sheath.

Sugar in Baby Food: A revealing chart shows how much sugar is added to baby food products in different countries, raising questions about nutrition standards.

Hypochondriac’s Origin: Originally, hypochondria was related to the upper abdomen region and was believed to be the source of various ailments.

Spartan Society: While Spartan warriors are legendary, they represented only about 6% of the population. The majority were slaves, making the elite status of Spartans even more striking.

Spy Kids: Alexander Foley, born in Canada, discovered his parents were KGB spies only after their arrest in 2010, a revelation that led to a legal battle over his citizenship.

3D-Printed Houses: The Crane WASP printer uses local materials like dirt to build houses in remote areas, offering a sustainable solution to Colombia’s housing crisis.

Each of these learnings not only sparks curiosity but also deepens our understanding of the world, from the microscopic to the macroscopic.



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Here at Gowing Life, we are keeping our fun record of everything we learn in 2024, be it longevity-related or…

02/09/2024

Recent research explores whether hyperbaric oxygen therapy (HBOT), a treatment that increases oxygen delivery to tissues, could improve physical fitness in older adults. A new study involving 63 participants, aged 70 on average, found that those who received 60 HBOT sessions over 12 weeks showed significant improvements in key fitness markers such as VO2max—an important measure of aerobic health—and myocardial blood flow, which relates to heart health.

The study suggests HBOT may stimulate beneficial changes in blood vessels and enhance mitochondrial function, potentially improving cardiorespiratory fitness. However, it is important to note the study's limitations, such as the possibility of placebo effects and the lack of a comparison to regular exercise. While HBOT might be useful for those unable to exercise regularly, further research is needed to fully understand its role in healthy ageing.



To the article:

Everyday our team of researchers in Oxford are inundated with scientific, and medical research articles that have the potential to improve health, wellbeing, and longevity.