11/10/2025
Why I use non fluoride toothpaste! There's more than enough of it in the water = it seems to make bones more brittle . Many women are reported to say ' I heard it break and then I fell'!
NEW STUDY:
"Fluoride exposure and its effects on human health are controversial and highly debated.
We used existing literature to quantify the dose-response relation between fluoride exposure and bone health, focusing on fracture risk and bone mineral density (BMD).
We conducted a systematic review and dose-response meta-analysis by searching literature in online databases (MEDLINE/PubMed, Embase and Web of Science) up to August 26, 2025, and by pooling results of studies examining fluoride exposure and its associations with bone health outcomes, namely fracture risk and BMD. We also conducted stratified analyses by sex, age, and fracture site.
We found a non-linear, positive relation between fluoride exposure and fracture risk, with an indication of an approximate threshold around 1.5 mg/L of fluoride in drinking water and a nearly linear increasing fracture risk above that concentration.
Among females aged over 50 years, an association of drinking water fluoride with fragility fracture risk started as early as around 0.5 mg/L.
Conclusions
This study indicates increased risk of fractures with fluoride exposure > 1.5 mg/L in drinking water, with an enhanced susceptibility in postmenopausal females.
These findings, which appear consistent with those yielded by recent pooled analysis related to other endpoints in children, may be helpful in assessing the risk-benefit profile for fluoride exposure."