05/07/2024
Even more potential advancements in treating osteoarthritis (OA)?
A recent study delved into the potential of mature adipocyte-derived dedifferentiated fat cells (DFATs) in treating osteoarthritis (OA).
The study, conducted on rats, revealed that intra-articular injections of DFATs significantly halted cartilage degeneration from artificially induced osteoarthritis, showcasing their chondroprotective properties!
Moreover, in vitro experiments showed that DFATs, derived from both infrapatellar fat pad (IFP) and subcutaneous adipose tissue (SC), upregulated key genes involved in immune regulation and cartilage protection under inflammatory stimulation. This suggests DFATs as a promising cellular resource for OA treatment, with potential implications for future therapies.
Read more of this exciting development here: https://bit.ly/3yK4FAh