UK MS Register

15/09/2025

Could a citrus extract improve Cognition and Fatigue in Multiple Sclerosis (MS)?

A team from Swansea University are conducting research on the effects of citrus extract supplementation on cognition and fatigue in people diagnosed with Relapsing Remitting Multiple Sclerosis (RRMS).

If you have RRMS and would like to register your interest to take part in this study please follow this link: https://research.sc/participant/login/dynamic/96F5A07C-108E-4576-B01B-86F6FC57A6EA

09/09/2025

A new study using data from the UK MS Register has found that a number of people living with MS experience significant cognitive issues, despite having minimal physical symptoms. The authors suggest that this "underscores the importance of cognitive assessment in MS", as these problems can often be underdiagnosed and left unaddressed.

09/09/2025

📢 Exciting news from the UK MS Register!

A new research paper has just been published in Nature Communications that used data from thousands of people with MS who take part in the Register. 🙌

The study found a new subtype of MS that mainly affects thinking and memory, rather than physical symptoms — something that hasn’t been clearly identified before.

This discovery shows just how powerful online tools and large-scale participation can be in helping us better understand MS. Thank you to everyone who has contributed to the UK MS Register — this research wouldn’t be possible without you! 💙

🔬 Read more here:

Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment Cognitive tests deployed using the UK MS Register have been used in important new research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London. ...

27/08/2025

In case you didn't know...the UK MS Register host the MS Pregnancy Register.

The MS Pregnancy Register was launched in 2021 with the aim of learning more about the experiences of women in the UK with , and their fertility journeys.

You can read the latest update from the Pregnancy Register here 👇

https://blog.msregister.org/ms-pregnancy-register-update-summer-2025/

15/08/2025

📣 Out Now 📣 the latest episode of the Multiple Sclerosis Trust podcast, this time featuring the UK MS Register's Dr Rod Middleton.

This episode focuses on sleep disruption in and night-time symptoms. Listen to the episode to hear Rod discussing the Register's recent collection of sleep data from participants, and what this could mean for research into MS and sleep.

We were very excited to be involved with this podcast - thank you to Helena Jidborg Alexander and all at the MS Trust 🩵

If you live with multiple sclerosis and struggle to get a good night sleep, this episode is for you. We uncover the hidden impact of night-time MS symptoms, from nerve pain, spasms, and restless legs to bladder urgency, burning sensations, and cold feet and explore why these issues often seem to wor...

13/08/2025

RefuelMS is a new clinical trial that is testing a digital, app-based treatment for fatigue. Fatigue is one of the most common symptoms of MS. 💤

Data from the UK MS Register shows 90% of people with MS experience fatigue. But less than a third of people have been offered treatment for their fatigue as part of their routine care.

Recruitment is open now, currently on an invitation only basis. Invitations will be sent through the UK MS Register.

Find out more about RefuelMS: https://mssoc.uk/3INEP3r

07/08/2025

Today the UK MS Register were delighted to host Ceri from the MS Society Cymru who visited our offices at Swansea University along with a fantastic group of fundraisers and supporters of the MS Society UK 🧡

We enjoyed an informative morning visiting the labs with Dr Owain Howell and hearing from his PhD students about the incredible MS research being carried out here. Dr Rod Middleton then gave the group an insightful introduction to the MS Register 📊

Thank you to Ceri and all our guests for visiting and for your interest in our work! 🙂

01/08/2025

01/08/2025

We have officially started the Refuel MS clinical trial🎉

In this randomised controlled trial, we will be looking at how effective the Refuel MS intervention is compared to usual care 🔎

Recruitment will initially be through invitation only via the UK MS Register. If you would like to hear more, make sure you’re signed up to the UK MS Register📝

We want to say a big thank you to everyone who has helped us reach this milestone 🧡

We’re very excited for this chapter, follow along for updates as the trial progresses, and for future recruitment calls!

31/07/2025

We have a new blog now available on our website. This time we look back on day in June:

On Friday 20th June we celebrated day. The aim of this special calendar day is to get as many people as possible wearing red to show their support and appreciation for everyone who participates in or undertakes research. It’s a fantastic opportunity to highlight the incredible work t...

31/07/2025

Join us for our Using a wheelchair to gain independence webinar!

We’ll be joined by Pete Donnelly, a wheelchair user of 19 years. He believes that he’s gained valuable skills from getting around in a wheelchair ♿

He'll share his knowledge of types of wheelchairs and skills to develop.

📆 Thursday 14 August
⏰ 6.30pm

Find out how to register here: https://mssoc.uk/3UrAxkE