25/11/2025
Arthrosamid® Knee Injections: A new option for treating knee arthritis
If you suffer from knee arthritis, you know how much it can affect your daily life — from walking the dog to climbing stairs or simply getting an uninterrupted night’s sleep. While treatments such as physiotherapy, steroid injections, and replacement surgery can help, many people are looking for longer-lasting relief without the risks or long recovery time of surgery. That’s where Arthrosamid® comes in — a new and clinically proven treatment for knee osteoarthritis that’s now available in the UK, including at Yeovil Orthopaedic Clinic.
What Is it?
Arthrosamid® is a non-biodegradable polyacrylamide hydrogel injection developed specifically for the treatment of knee osteoarthritis. Unlike other types of injections (such as steroid or hyaluronic acid), Arthrosamid® is not absorbed or broken down by the body. Instead, it becomes a permanent part of the joint lining, acting as a soft, cushioning layer inside the knee.
This means that, rather than just providing temporary pain relief, Arthrosamid® has the potential to help improve joint pain and function for the longer term (even several years)
How does it work?
In osteoarthritis, the smooth cartilage that normally covers the ends of your bones breaks down and wears away, with resulting inflammation leading to stiffness, swelling, and pain. Arthrosamid® works by:
• Lubricating the joint: improving movement and reducing friction.
• Acting as a cushion: absorbing pressure and shock inside the knee.
• Reducing inflammation and pain (by reducing synovitis): many patients report significant pain relief within weeks.
Clinical studies have shown sustained improvement in pain and quality of life for up to 3 years following a single injection.
The Procedure
The Arthrosamid® injection is a day-case, non-surgical procedure performed under local anaesthetic.
The whole process usually takes around 20–30 minutes:
1. Tablet antibiotics are given to reduce the risk of infection
2. The skin around the knee is numbed with local anaesthetic
3. Under ultrasound guidance, the Arthrosamid® gel is carefully injected into the knee joint cavity by a specialist knee surgeon trained in this technique
4. You can walk immediately afterwards and return to normal activities within a day or two (although strenuous activity should be avoided for the first few weeks)
There’s no hospital stay, no general anaesthetic, and no lengthy recovery period. Patients may experience mild discomfort for a few days after the procedure requiring standard painkillers.
Who can benefit?
Arthrosamid® may be suitable if you:
• Have been diagnosed with knee osteoarthritis - all grades of knee arthritis can be considered, but the best response rates are in patients under 70 years old with moderate arthritis who have post-activity swelling / inflammation
• Are no longer getting relief from physiotherapy, painkillers, or other types of injection
• Wish to delay or avoid knee replacement surgery
Your suitability will be assessed through a detailed consultation and examination, supported by X-rays and / or MRI scans.
What are the benefits?
• Long-lasting pain relief – around 80% of patients have a positive response, with many reporting improvements in pain and function lasting years
• Better mobility and quality of life – move more freely, with less discomfort
• Minimally invasive – no surgery or scars, out-patient treatment
• Clinically proven and CE-marked for safety and effectiveness, with a safety profile established over 20 years
Is it right for you?
Every patient - and every knee - is different and needs careful individual assessment. If you’ve been struggling with the symptoms of knee arthritis and are looking for a modern, evidence-based treatment that has the potential to offer lasting relief, Arthrosamid® may be an excellent option.
Book a Consultation
If you’d like to learn more about Arthrosamid® knee injections or discuss whether this treatment is right for you, please get in touch with Yeovil Orthopaedic Clinic to arrange a consultation and receive information on self-pay treatment packages. Together, we can explore the most effective, personalised options to reduce pain and help you stay active.
Ben Lankester, November 2025