Center for Clinical Epidemiology and Outcomes (CLEO) Research was established in 2011 with the joint collaboration of the First and Second University Departments of Pediatrics of the "Aghia Sophia" and "P. & A.
22/04/2026
Healthy environments create the foundation for healthy populations.
Air quality, climate patterns, water safety, and biodiversity all influence how diseases emerge, spread, and affect communities. Understanding these links is becoming increasingly important for public health research.
At CLEO, studying the broader determinants of health helps inform strategies that protect both people and healthcare systems.
This Earth Day, we are reminded that safeguarding our planet is also an investment in the long-term health and well-being of societies worldwide.
20/04/2026
You cannot reduce hospital-acquired infections if you cannot see them. Surveillance systems are one of the most powerful, and sadly often underestimated, tools in patient safety.
When hospitals systematically collect and analyze infection data, they can:
• identify outbreaks earlier
• track transmission pathways
• evaluate the effectiveness of interventions
Evidence from multiple healthcare systems shows that structured surveillance programs are strongly associated with lower HAI rates. Data does not prevent infections on its own. But without it, prevention becomes guesswork.
How widely adopted are digital surveillance systems in your healthcare environment?
08/04/2026
🌸 Our team will be taking a short break over the Easter holidays!
Wishing everyone a peaceful Easter and a well-deserved pause, especially to those across healthcare who continue their work throughout this period.
07/04/2026
🌍 April 7th - Global Health Day
Health is shaped by more than medical care alone. It reflects the conditions people live in, the systems that support them, and the evidence that guides decisions in healthcare.
From infection prevention to the evaluation of new health strategies, research plays a vital role in strengthening public health and improving patient outcomes.
On this World Health Day, we highlight the importance of evidence-based approaches that help build healthier communities and more resilient healthcare systems.
We join the global call to stand with science and work together for health, recognizing that collaboration and evidence are key to addressing today’s health challenges and those yet to come.
03/04/2026
We are proud to support the dialogue on the future of healthcare!
At Star Forum 2026, CLEO’s Founder & Scientific Director, Theoklis Zaoutis, participated in a compelling session on "The Human-Centric Nature of Medical Science." Professor Zaoutis shared his insights on the importance of Infection Prevention in healthcare.
He highlighted the statistical success of the GRIPP-SNF program, as this 5-year initiative, supported by the Stavros Niarchos Foundation, is proving that systematic intervention works!
Bringing these high-stakes public health themes to a public stage like Star Forum is essential for driving the national dialogue on patient safety and medical excellence. 👏
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03/04/2026
Με ιδιαίτερη χαρά και αίσθημα ευθύνης, το CLEO στήριξε τις εργασίες του 4ου Πανελλήνιου Συνεδρίου Παιδιατρικής και Εφηβικής Ιατρικής.
Για εμάς, η ενίσχυση τέτοιων επιστημονικών πρωτοβουλιών είναι υψίστης σημασίας. Η Παιδιατρική και η Εφηβική Ιατρική βρίσκονται στον πυρήνα της δημόσιας υγείας, και η διαρκής ενημέρωση γύρω από τις νέες εξελίξεις είναι το «κλειδί» για τη διασφάλιση της ποιότητας ζωής των παιδιών και των εφήβων μας!
26/03/2026
Patient safety begins long before hospital admission.
Vaccination, early diagnosis, responsible antibiotic use, and public awareness all reduce avoidable burden on hospitals.
Infection prevention is not confined within hospital walls. It is a shared responsibility across communities, primary care, and public health.
We should always remember: stronger systems begin upstream!
16/03/2026
Data alone does not improve care, but what actually matters is what we do with them.
Surveillance becomes powerful when it feeds back into practice: when teams see trends, understand risks, and adapt in real time. From infection rates to hand hygiene compliance, data translate into action when they are timely, clear, and trusted.
That is how numbers become safer bedsides!
11/03/2026
Frontline teams know where risks truly lie. Empowerment means listening, trusting, and equipping them to lead improvement.
Change is strongest when it rises from within, as patient safety is never achieved alone. It emerges through collaboration between clinicians, administrators, educators, and public health professionals.
Shared purpose multiplies impact. Every day, healthcare professionals prevent harm that no one will ever see. That quiet work saves lives. To all who protect patients through vigilance, care, and commitment, thank you! Your impact is real, even when invisible.
04/03/2026
HPV is often invisible. Most infections cause no immediate symptoms, and many people never realize they have been exposed. Yet its long-term consequences can occur.
What makes HPV unique is not only how common it is, but how effectively we can prevent its most serious outcomes. Vaccination interrupts transmission, protects across genders, and reduces the burden of multiple cancers long before disease ever appears.
This is prevention at its most powerful: acting early, before risk becomes reality. So that we can have one less worry, that is the theme for 2026!
At CLEO, we support HPV vaccination as a public health investment in future wellbeing. It is not only about avoiding illness, but about giving the next generation the freedom to grow without carrying a preventable risk.
28/02/2026
For millions of people worldwide, living with a rare disease is a daily reality shaped by uncertainty, delayed diagnosis, and limited access to care.
Rare diseases may be individually uncommon, but together they affect entire families, health systems, and communities. Behind every diagnosis is a person navigating complex needs, and often, long journeys toward answers.
Our team at CLEO recognizes that equity in healthcare means ensuring that no patient is overlooked because their condition is rare. Strong surveillance, data, research, and collaboration are essential to shorten diagnostic pathways and improve outcomes.
Awareness is the first step. Evidence is the foundation. Compassion is what turns both into meaningful care.
On Rare Disease Day, we stand with patients, families, and professionals working to make the invisible visible and to ensure that rarity never means neglect.
19/02/2026
The invisible impact: Some of the most meaningful results in healthcare are the ones we never see.
An infection that does not occur, a complication that never develops or a patient who goes home sooner than expected.
Prevention works quietly. Yet its impact is profound: fewer adverse events, less antibiotic use, preserved ICU capacity, better outcomes. Infection prevention is not about adding tasks. It is about removing harm. And every prevented infection is a success story.
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CLEO Κέντρο Κλινικής Επιδημιλογίας και Έκβασης Νοσημάτων
Το Κέντρο Κλινικής Επιδημιολογίας και Έκβασης Νοσημάτων (CLEO) ιδρύθηκε το 2011 υπό την αιγίδα της Α’ & Β’ Πανεπιστημιακής Παιδιατρικής Κλινικής της Ιατρικής Σχολής του Πανεπιστημίου Αθηνών, με δωρεά του Ιδρύματος «Σταύρος Νιάρχος». Το όραμα του CLEO ήταν η βελτίωση της ασφάλειας των ασθενών και της ποιότητας των παρεχόμενων υπηρεσιών υγείας στα ελληνικά νοσοκομεία με έμφαση στην πρόληψη των νοσοκομειακών λοιμώξεων και στην ορθολογική χρήση των αντιβιοτικών. Από τον Οκτώβριο του 2014 το CLEO λειτουργεί ως Αστική μη Κερδοσκοπική Εταιρία.
Από τον Ιούλιο του 2012 έως τον Δεκέμβριο του 2015, οι δράσεις του CLEO στόχευαν στην πρόληψη των νοσοκομειακών λοιμώξεων και στην ορθή χρήση των αντιβιοτικών στα δύο Γενικά Νοσοκομεία Παίδων της Αθήνας, «Η Αγία Σοφία» και «Παναγιώτη και Αγλαΐας Κυριακού». Πιο συγκεκριμένα, επικεντρώθηκαν στο σχεδιασμό και την εφαρμογή εκπαιδευτικών παρεμβάσεων για τη διάδοση των κατάλληλων πρακτικών με στόχο τη βελτίωση της ποιότητας των παρεχόμενων υπηρεσιών υγείας και την υιοθέτηση διεθνώς καθιερωμένων κατευθυντήριων οδηγιών στην καθημερινή κλινική πράξη. Η ερευνητική ομάδα του CLEO συνεργάστηκε με εξειδικευμένο διδακτικό, ερευνητικό, ιατρονοσηλευτικό και διοικητικό προσωπικό, από την Ελλάδα και το εξωτερικό, για να σχεδιάσει και να αναπτύξει αυτές τις παρεμβάσεις, να τις εφαρμόσει και να εκτιμήσει την αποτελεσματικότητά τους.
Τα ενθαρρυντικά αποτελέσματα του προγράμματος παρείχαν αισιοδοξία για τη δυνατότητα ελέγχου και πρόληψης των νοσοκομειακών λοιμώξεων και κατ’ επέκταση της έκβασης της υγείας των ασθενών. Η αυξανόμενη πεποίθηση ότι οι νοσοκομειακές λοιμώξεις μπορούν να προληφθούν σε ένα μεγάλο ποσοστό, έχει εγείρει το ενδιαφέρον αρκετών μονάδων υγείας, οι οποίες επιθυμούν να συμμετάσχουν στην επέκταση του προγράμματος. Από τον Ιανουάριο του 2016, το CLEO διευρύνει τα πεδία δράσης του, τόσο στα νοσηλευόμενα παιδιά όσο και στους νοσηλευόμενους ενήλικες σε όλη την Ελλάδα. Στα πεδία δράσης του εντάσσονται:
Η επιτήρηση και η πρόληψη των πιο συχνών νοσοκομειακών λοιμώξεων.
Η επιτήρηση και η βελτίωση της συμμόρφωσης σε επιλεγμένες πρακτικές πρόληψης.
