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12/05/2026
在犬隻最常見的口腔腫瘤中，鱗狀細胞癌 (SCC) 及纖維肉瘤 (FSA) 的發病率僅次於黑色素瘤。
這兩類腫瘤均具有高度的局部侵襲性，會深入浸潤口腔周邊組織，引發嚴重的疼痛與不適感。雖然其遠端轉移率相對較低（約 10-20%），但若未採取治療，腫瘤在口腔內的持續生長最終會導致犬隻進食或飲水困難，嚴重影響生活品質，多數病例最終因此面臨死亡或需考慮安樂死。
鱗狀細胞癌與纖維肉瘤必須透過組織切片檢查 (Biopsy)來診斷。
治療方案通常為廣泛性手術切除，過程中通常需要移除大部分的上頜骨或下頜骨。
雖然手術是最有效的治療方式，但鱗狀細胞癌與纖維肉瘤的復發率仍偏高，約有 20–50% 的病例會復發。若手術未能完全切除，可考慮手術配合放射治療以提高療效。
若能成功進行完整的腫瘤切除，大部分患有纖維肉瘤或鱗狀細胞癌的犬隻可望痊癒。
對於無法透過手術切除的晚期鱗狀細胞癌，可利用化學治療、標靶治療及放射治療的綜合治療方案，約 60-80% 的鱗狀細胞癌對藥物或放射治療有良好反應。
雖然這些腫瘤屬於嚴重疾病，但若能及早診斷並採取適當治療，許多犬隻仍有機會獲得更長久且舒適的生活品質。
Squamous cell carcinoma (SCC) and fibrosarcoma (FSA) are dogs' second most common mouth tumours after melanoma.
SCC and FSA are both locally aggressive cancers that infiltrate the tissues around the mouth, causing pain and discomfort. The metastatic rate is however quite low around 10-20%. Most dogs that are not treated will die or be euthanized due to the progression of cancer in the mouth once it causes difficulty or inability to eat or drink.
Diagnosis of SCC and fibrosarcoma is obtained by tissue sample biopsy.
The treatment of choice is wide surgical resection, including a large portion of the lower or upper jaw.
Despite surgery being the most effective treatment, the recurrence rate for SCC and even more fibrosarcoma is reasonably high with~ 20-50% of cases experiencing recurrence.
Surgery followed by radiotherapy can be more effective if a complete resection is not achieved.
Most dogs with completely resected fibrosarcoma or SCC can be cured.
Advanced non-resectable SCC can be successfully treated with a combination of various chemotherapeutic targeted therapies and/or radiotherapy.
Around 60-80% of SCCs respond to medical treatment and/or radiotherapy.
While these cancers are serious, timely diagnosis and appropriate treatment can give many dogs a chance at a longer and more comfortable life.
