Cardiovascular Innovations and Applications

Cardiovascular Innovations and Applications A platinum open access & the official journal of the Great Wall International Congress of Cardiology

Cardiovascular Innovations and Applications (CVIA) publishes focused articles and original clinical research that explore novel developments in cardiovascular disease, effective control and rehabilitation in cardiovascular disease, and promote cardiovascular innovations and applications for the betterment of public health globally. The journal publishes basic research that has clinical applicability in order to promote timely communication of the latest insights relating to coronary artery disease, heart failure, hypertension, cardiac arrhythmia, prevention of cardiovascular disease with a heavy emphasis on risk factor modification. CVIA also welcomes commentaries, case studies and reports, letters to the editor, methodology papers related to clinical trials, education and training articles, techniques and videos. CVIA was founded on the occasion of the 25th anniversary of the GW-ICC in 2014 by Professor Dayi Hu, president of the GW-ICC and past president of the Chinese Society of Cardiology, and C. Richard Conti, MD, a past president of the American College of Cardiology and former Editor of Clinical Cardiology. The GW-ICC is one of the largest congresses in the Asian-Pacific region and is the most comprehensive and influential academic conference on cardiology. Held as a regular annual conference since 1990, GW-ICC has provided a platform for continuing education in cardiovascular disease diagnosis, treatment, and technology training, through events that leverage the expertise of internationally renowned cardiologists and scholars from the United States, Europe and Asia. The journal is published by Compuscript on behalf of the World Journals (Beijing) Medical Technology Co., Ltd. Compuscript is an international company based in Shannon, Ireland.

This editorial discusses how integrating with –based models, such as Apo-CIII, IL-6, and vWF, could enhance timely di...
04/09/2025

This editorial discusses how integrating with –based models, such as Apo-CIII, IL-6, and vWF, could enhance timely diagnosis of , reduce subsequent burden and improve patient outcomes. King's College London

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Explore novel biomarkers and AI-driven models enhancing Transient Ischemic Attacks Diagnosis, improving early detection, risk stratification, and timely stroke prevention.

This review outlines strategies to enhance mitochondrial function, such as regulating biogenesis, promoting , using ant...
28/08/2025

This review outlines strategies to enhance mitochondrial function, such as regulating biogenesis, promoting , using antioxidants, modulating the calcium balance, and optimizing , providing new insights for treatment.

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This review highlights new targets and drugs to address mitochondrial dysfunction in diabetic cardiomyopathy (DCM) and slow its progression.

This case report highlights the successful total endoscopic transcatheter mitral valve-in-valve replacement using a sy...
26/08/2025

This case report highlights the successful total endoscopic transcatheter mitral valve-in-valve replacement using a system, combined with occlusion and , offering a safer alternative to redo sternotomy with improved outcomes.

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A case report on the use of a total endoscopic approach for TMVIV replacement with a J-valve system, combined with LAA occlusion and tricuspid valve repair.

A geometric multiscale model coupling a zero-dimensional (0D) lumped-parameter circulatory system model with a three-dim...
26/08/2025

A geometric multiscale model coupling a zero-dimensional (0D) lumped-parameter circulatory system model with a three-dimensional (3D) coronary artery model reconstructed from patient-specific imaging data identified wall shear stress (WSS) as a critical hemodynamic indicator for evaluating EECP effectiveness. Sun Yat-sen University 中山大学

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Geometric multiscale model provides mechanistic insights into the hemodynamic regulation during enhanced external counterpulsation (EECP) Coronary heart disease.

This study shows that blood ApoC-III, IL-6 & vWF, combined with clinical data via PanelomiX, can enhance accuracy in d...
21/08/2025

This study shows that blood ApoC-III, IL-6 & vWF, combined with clinical data via PanelomiX, can enhance accuracy in distinguishing (TIAs) from mimics, achieving 100% sensitivity in diagnosis. Joan Pont Montaner Universitat Autònoma de Barcelona Hospital Universitario Virgen Macarena

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This study identifies blood biomarkers (ApoC-III, IL-6, vWF) to improve diagnosis of transient ischemic attacks (TIAs) versus mimics.

Intravenous administration of after via distal transradial access significantly shortened the postoperative compress...
14/08/2025

Intravenous administration of after via distal transradial access significantly shortened the postoperative compression time and showed good safety, without drug-related adverse reactions, serious bleeding, or events. Peking Union Medical College / Chinese Academy of Medical Sciences

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Intravenous protamine sulfate reduces postoperative compression time after coronary angiography via distal transradial access (dTRA) while ensuring safety

In this study, differentially expressed microRNAs linked to key regulatory pathways in acute myocardial infarction were ...
07/08/2025

In this study, differentially expressed microRNAs linked to key regulatory pathways in acute myocardial infarction were identified, offering valuable insights for precise diagnostic strategies and personalized therapeutic approaches. Southern Medical University

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The study identifies 15 differentially expressed miRNAs in AMI, providing insights into their potential as early diagnostic biomarkers for ST-elevation myocardial infarction.

This commentary highlights the role of adipokines, like ANGPTL2, C1q/TNF-related proteins 3 and 9, Fibroblast growth fac...
31/07/2025

This commentary highlights the role of adipokines, like ANGPTL2, C1q/TNF-related proteins 3 and 9, Fibroblast growth factor 21, Osteopontin, and Tumor necrosis factor-alpha observed in the pathogenesis of heart failure. LCWU Lahore College for Women University

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Explore the role of adipokines in heart failure pathogenesis, including ANGPTL2, FGF21, and osteopontin, and their impact on prediction, diagnosis, and prognosis.

An editorial on a approach that provides a comprehensive understanding of the molecular mechanisms underlying and ...
30/07/2025

An editorial on a approach that provides a comprehensive understanding of the molecular mechanisms underlying and (AAA), highlighting the importance of routine AAA screening in COPD patients. Università degli studi di Trieste Mario Giovanni Gerardo D'Oria

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Editorial highlights a multi-omics approach to uncover genetic and molecular mechanisms in chronic obstructive pulmonary disease and abdominal aortic aneurysm.

This case study illustrates the complexity of managing severe mitral regurgitation in an older patient with multiple com...
24/07/2025

This case study illustrates the complexity of managing severe mitral regurgitation in an older patient with multiple comorbidities, and highlights the successful outcome of the percutaneous with the .

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First Italian case of percutaneous mitral valve repair with PASCAL Ace system in an elderly patient with a dislocated annuloplasty ring and severe regurgitation

This review summarizes the various factors contributing to the etiology of different (HF) types, current anti-inflam...
17/07/2025

This review summarizes the various factors contributing to the etiology of different (HF) types, current anti-inflammation therapies for HF, and lists the results of of anti-Inflammatory therapies in HF patients.

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Explore the role of inflammation in heart failure, its impact on prognosis, and current therapeutic strategies to improve clinical outcomes in HF management.

This study used a approach to provide a comprehensive understanding of the and molecular mechanisms underlying and...
17/07/2025

This study used a approach to provide a comprehensive understanding of the and molecular mechanisms underlying and (AAA), underscoring the importance of COPD as a potential risk factor for AAA.

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A multi-omics approach for comprehensive understanding of the genetic and molecular mechanisms underlying COPD and Abdominal Aortic Aneurysm

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Cardiovascular Innovations and Applications (CVIA) was founded on the occasion of the 25th anniversary of the GW-ICC in 2014 by Professor Dayi Hu, president of the GW-ICC and past president of the Chinese Society of Cardiology, who will serve as Founding Editor. C. Richard Conti, MD, a past president of the American College of Cardiology and former Editor of Clinical Cardiology, has recently been appointed Editor-in-Chief of the new journal, which will publish its first issue to coincide with the GW-ICC meeting in October 2015 in Beijing, China.