In a collection of writings on medical marijuana by 45 researchers, a literature review on the medicinal uses of Cannabis and cannabinoids concluded that established uses include easing of nausea and vomiting, anorexia, and weight loss; "well-confirmed effect" was found in the treatment of spasticity, painful conditions (i.e. neurogenic pain), movement disorders, asthma, and glaucoma. Reported but "less-confirmed" effects included treatment of allergies, inflammation, infection, epilepsy, depression, bipolar disorders, anxiety disorder, dependency and withdrawal. Basic level research was being carried out at the time on autoimmune disease, cancer, neuroprotection, fever, disorders of blood pressure. Medical cannabis is also used for analgesia, or pain relief. It is also reported to be beneficial for treating certain neurological illnesses such as epilepsy, and bipolar disorder. A recent study has also concluded that cannabinoids found in Cannabis might have the ability to prevent Alzheimer's disease.[105] THC has been shown to reduce arterial blockages.[106]
Another potential use for medical cannabis is movement disorders. Cannabis is frequently reported to reduce the muscle spasms associated with multiple sclerosis
According to the UK medical journal The Lancet, Cannabis has a lower rate of dependence compared to both nicotine and alcohol.any Cannabis withdrawal symptoms are typically mild and are never life-threatening. Psychoactive effects
The psychoactive effects of cannabis, known as a "high", are subjective and can vary based on the individual and the method of use.Cannabis is often considered an atypical, unique and sometimes paradoxical psychotropic due to its vast and sometimes contradictory array of effects. The subjective experience induced by using cannabis can be considered stimulatory and yet also sedative or depressant, while also having markedly mild psychedelic and even dissociative characteristics.Some effects may include a general alteration of conscious perception, euphoria, feelings of well-being, relaxation or stress reduction, increased appreciation of humor, music or the arts, joviality, metacognition and introspection, enhanced recollection (episodic memory), increased sensuality, increased awareness of sensation, increased libido,[25] creative, abstract or philosophical thinking, disruption of linear memory and paranoia or anxiety. Anxiety is the most commonly reported side effect of smoking marijuana. Between 20 and 30 percent of recreational users experience intense anxiety and/or panic attacks after smoking cannabis.[26]Cannabis also produces many subjective and highly tangible effects, such as greater enjoyment of food taste and aroma ("the munchies"), an enhanced enjoyment of music and comedy, and marked distortions in the perception of time and space (where experiencing a "rush" of ideas from the bank of long-term memory can create the subjective impression of long elapsed time, while a clock reveals that only a short time has passed). At higher doses, effects can include altered body image, auditory and/or visual illusions, pseudo-hallucinatory or (rarely, at very high doses) fully hallucinatory experiences, and ataxia from selective impairment of polysynaptic reflexes. In some cases, cannabis can lead to dissociative states such as depersonalization[27][28] and derealization;[29] such effects are most often considered desirable, but have the potential to induce panic attack and paranoia in some unaccustomed users.