29/05/2026
Genetically Transmitted Skin Diseases – Part 3
Genetic skin disorders can affect skin structure, pigmentation, barrier function, and overall health. Hailey–Hailey Disease causes recurrent blisters and painful erosions in skin folds, especially in areas of friction. Oculocutaneous Albinism results from reduced melanin production, leading to light skin, hair, and vision-related challenges. Incontinentia Pigmenti is a rare genetic disorder characterized by distinctive skin changes that evolve through different stages over time. Cutis Laxa causes loose, sagging skin due to defects in elastic fibers. Netherton Syndrome presents with red, scaly skin, fragile hair, and increased susceptibility to allergies and infections. Early diagnosis, regular follow-up, and multidisciplinary care can significantly improve quality of life and long-term outcomes.