Apollo Medicine, Indraprastha Apollo Hospitals, Sarita Vihar, Delhi (2026)

03/01/2026

Accelerated atherosclerosis is a key driver of vascular complications in diabetes. Endothelial dysfunction and heightened platelet hyperactivity only make things worse.
📊 Platelet indices—MPV, PDW, P-LCR, PCT—reflect these changes and are often elevated, especially when complications are present.
🔍 These simple, inexpensive tests may help assess glycaemic control and complication risk, but more longitudinal studies are needed to establish their clinical utility.
📖 Read the full article:

An accelerated atherosclerotic process is a significant contributor to the development of vascular complications in diabetes. Endothelial dysfunction and height...

03/01/2026

Diabetes and OSA frequently coexist—and obesity plays a key role in driving both. OSA, marked by repeated nighttime airway obstruction and hypoxia, is highly prevalent among individuals with type 2 diabetes (T2DM). Conversely, T2DM itself can raise the risk of OSA through obesity, inflammation, and autonomic imbalance.
💡 Management insights:
• CPAP therapy can enhance insulin sensitivity and improve cardiovascular outcomes
• Newer anti-obesity medications show promise in reducing OSA severity and improving metabolic health
📖 Read the full article: https://doi.org/10.1177/09760016251329043
👨‍⚕️ Authors:

Diabetes and obstructive sleep apnoea (OSA) are interconnected chronic conditions. The increasing prevalence of obesity drives the pathogenesis of these interre...

02/01/2026

The rising burden of metabolic diseases—obesity, prediabetes, and Type 2 diabetes—is bringing renewed attention to “non-classical” comorbidities. One such condition is male hypogonadism, reported in nearly one-fourth of men with diabetes across studies in India and globally.
Our review highlights:
🔍 A bidirectional link between T2DM and hypogonadism, with each worsening the other
🧪 The importance of careful clinical evaluation, including hormonal testing (FSH, LH, testosterone, SHBG)
⚠️ The need to differentiate age-related andropause from diabetes-related hypogonadism
👨‍⚕️ The role of endocrinology referral for accurate diagnosis and management
📌 On testosterone therapy:
While some studies show metabolic benefits, concerns remain regarding prostate risks, elevated haematocrit, and cardiovascular events. Current Endocrine Society guidelines advise against testosterone solely for metabolic improvement, whereas the Indian IDEA group supports individualised, patient-centred decisions.
As diabetes rises, recognising and evaluating hypogonadism becomes crucial for optimal men’s health and holistic metabolic care.
📖 Read the full article: https://doi.org/10.1177/09760016251332088
👨‍⚕️Authors:

Objectives: The spectrum of metabolic disease, including obesity, prediabetes and Type 2 diabetes mellitus (T2DM), is increasing globally at an alarming rate. I...

02/01/2026

As diabetes continues to rise globally, high-quality communication between patients and healthcare providers has never been more important. Our recent review highlights how diabetes-specific communication can improve long-term outcomes, enhance patient satisfaction, and reduce complications.
📚 What the literature shows:
• Strong patient-provider communication improves overall quality of care
• Bi-directional dialogue is often lacking in busy outpatient settings
• There is a crucial need to integrate communication skills training into the medical curriculum
🚀 The way forward:
Empowering medical students with communication skills, adopting multidisciplinary care models, and leveraging technologies like AI can significantly elevate diabetes management.
Better conversations lead to better outcomes—let’s make communication a core competency in diabetes care.
📖 Read the full article: https://doi.org/10.1177/09760016251328407
👨‍⚕️ Authors:

Objectives: Effective, high-quality communication remains a cornerstone in the management of diabetes mellitus (DM). This review addresses how effective communi...

31/12/2025

Diabetes has long been viewed as a controllable yet incurable chronic disease. But emerging evidence is reshaping this perspective—highlighting the promising concept of diabetes remission, where individuals achieve normoglycaemia without medication.
🔍 What our review found:
• Lifestyle change, intensive physical activity, early insulin therapy, and bariatric/metabolic surgery can lead to remission in Type 2 diabetes
• Early-stage interventions show higher remission rates
• Key mechanisms include improved insulin sensitivity, β-cell recovery, and weight loss
• Remission is encouraging—but not a permanent cure; relapse is possible
💡 Takeaway:
Diabetes remission represents a paradigm shift, moving from lifelong management to potential short-term control. Early intervention, sustained lifestyle modification, and regular monitoring are crucial for success.
📖 Read the full article: https://doi.org/10.1177/09760016251323727
👨‍⚕️Authors:

Background and Aim: Diabetes is a chronic metabolic disorder with increasing prevalence and mortality. Historically it has been considered as a controllable but...

30/12/2025

Hyperglycaemia—both chronic (via HbA1c) and stress-induced—plays a crucial role in determining outcomes among critically ill patients. Emerging markers like the glycaemic gap and stress hyperglycaemia ratio (SHR) offer even deeper insights.
📊 Our prospective study of 200 ICU patients in South India found:
• Higher glycaemic gap and SHR strongly predicted 30-day mortality
• Cutoffs of 45.49 mg/dL (glycaemic gap) and 1.355 (SHR) showed high sensitivity & specificity
• Elevated values were linked to longer ICU stays, need for mechanical ventilation, and renal replacement therapy
💡 Conclusion:
Glycaemic gap and SHR are promising, reliable markers for assessing severity and guiding management in critically ill patients—particularly valuable in resource-limited settings.
📖 Read the full article: https://doi.org/10.1177/09760016251326342
👨‍⚕️ Authors: ,
Sage India Apollo Hospitals

Introduction: Hyperglycaemia, both chronic and stress-induced forms, plays a significant role in determining outcomes for critically ill patients. Chronic hyper...

30/12/2025

Pigmented villonodular synovitis (PVNS) is rare but potentially aggressive—especially its diffuse form (DPVNS), which can involve the entire joint and progress to severe damage if untreated.
📌 Our case report:
A patient with biopsy-proven DPVNS underwent postoperative radiotherapy following surgical excision.
✅ Outcome: At 48 months, she remains disease-free with markedly improved joint function.
🔎 Key Insight: When complete excision is uncertain, postoperative radiotherapy offers better local control, low morbidity, and improved functional outcomes—making it an important consideration in managing DPVNS.
📖 Read the full article: https://doi.org/10.1177/09760016241284354
👨‍⚕️Authors:

Background and Aims: Pigmented villonodular synovitis (PVNS) is an uncommon but aggressive proliferative process affecting the synovium. Diffuse pigmented villo...

29/12/2025

Rhabdomyosarcoma (RMS) remains the most common soft tissue sarcoma in children, yet often goes unrecognised due to its resemblance to common head-and-neck conditions.
Our recent report describes an 8-year-old child with a midline, painless chin swelling—later diagnosed as RMS. Timely clinical suspicion enabled successful transoral resection, followed by chemotherapy, resulting in complete cure with no recurrence.
🔎 Takeaway: Even though rare, RMS must be considered in the differential diagnosis of rapidly enlarging, painless head-and-neck masses. Early identification and prompt treatment are crucial for favourable outcomes.
📖 Read the full article: https://doi.org/10.1177/09760016241283114
👨‍⚕️ Authors:

Background and Aims: Rhabdomyosarcoma (RMS) is the most common subtype of soft tissue sarcoma (STS) in children. Early diagnosis is the most favourable prognost...

29/12/2025

Hearing impairment remains the most common sensory deficit in humans, with genetics playing a major role in many cases. Our latest review explores the rapidly advancing field of genomics-driven research aimed at understanding and treating hereditary hearing loss.
📚 What we reviewed:
A comprehensive search across Scopus, PubMed, Medline, and Google Scholar focusing on recent breakthroughs in gene therapy for hearing loss.
✨ Key Highlights:
• Next-generation sequencing is transforming the diagnosis of genetic hearing impairment
• Screening strategies help identify shared mutations within affected groups
• Emerging gene delivery methods—viral & non-viral—show promise in restoring or preserving hearing
🎯 Takeaway:
With rapid technological progress, gene therapy stands as a promising future therapeutic option for hearing loss. Advances in targeted delivery and genetic correction are bringing us closer to meaningful clinical applications.
📖 Read the full article: https://doi.org/10.1177/09760016241286276
👨‍⚕️Authors:

Background: Hearing impairment is the most prevalent sensory deficiency among humans. Scientists have been actively studying the genetic factors behind human he...

27/12/2025

Visuals have always shaped science—from Darwin’s evolutionary trees to today’s digital designs. Our recent review explores how Graphical Abstracts (GA) and Infographics (IG) are reshaping research communication in the modern era.
📚 What we did:
A comprehensive review (April 2024) across PubMed, Scopus, Embase, and Google Scholar, along with representative GA and IG examples from Apollo Medicine.
✨ Key Insights:
• GA and IG improve comprehension, engagement, and retention
• They bridge the gap between researchers and the public
• Strategic layouts, colour cues, and interactive elements make complex data clearer and more appealing
🎯 Takeaway:
As visuals become more immersive and interactive, the challenge is to stay accurate without oversimplifying. GA and IG are powerful tools that make scientific findings more accessible—paving the way for a more informed and engaged audience.
📖 Read the full article: https://doi.org/10.1177/09760016241281426
👨‍⚕️ Authors:

Background and Aims: Historically integral to science, visual elements like Darwin’s evolutionary trees have evolved with technological advancements, leading to...

27/12/2025

Frequent hospital visits, joint stiffness, and treatment challenges often affect the quality of life (QOL) of boys with haemophilia. Our twin-centre study evaluated how a structured prophylaxis programme can make a difference—and the findings were encouraging.
✨ What we found:
• Majority had Haemophilia A (88%)
• Good adherence to prophylaxis in 66%
• QOL scores improved from 45.6 to 64.3 after four months
• Significant gains were seen across multiple domains
Prophylaxis clearly plays a vital role in enhancing day-to-day well-being and independence for children with haemophilia. 💙
📖 Read the full article: https://doi.org/10.1177/09760016241286274
👨‍⚕️Authors:

Background and Aims: Quality of life (QOL) of boys with haemophilia was severely affected due to many reasons like frequent hospital visits and joint stiffness....

26/12/2025

During the COVID-19 pandemic, parents of children with autism faced major challenges in accessing therapies. Our study explored how effective online, parent-mediated, home-based interventions could be—and the results were encouraging.
✨ What we found:
• Most parents reported improvement in their child’s language and play skills
• 88% felt confident delivering the programme
• 85% found the home-based plan easy to implement
• Parents appreciated the format and requested more follow-up teleconsultations
This study highlights just how adaptable and resilient caregivers truly are. 💙

📖 Read the full article: https://doi.org/10.1177/09760016241281433
👨‍⚕️ Authors:

Background and Aims: During the COVID-19 pandemic, many caregivers of children with autism faced significant challenges when it came to providing interventions....

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