03/04/2025
Why cancer patients receiving chemotherapy experience excessive cold or hot flushes ??? Read the article published in Indian Express based on my interview with the team.
https://indianexpress.com/article/lifestyle/health/hina-khan-feeling-extreme-cold-shivers-chemotherapy-side-effects-experts-9908921.
Chemotherapy can affect the body’s ability to regulate temperature, leading to sensations of excessive cold or heat. This occurs due to various factors, including direct interference with the brain’s temperature control mechanisms, autonomic nervous system dysfunction, peripheral neuropathy, and anemia. Some patients experience cold intolerance, while others may have hot flashes and night sweats.
Around 30-40 per cent of patients undergoing chemotherapy report some form of temperature dysregulation. However, it is not a universal symptom.The severity and type of temperature fluctuations can vary based on the specific chemotherapy drugs used, the patient’s overall health, nutritional status, and the presence of infections. In some cases, chemotherapy-induced nerve damage (neuropathy) can lead to a persistent feeling of cold, particularly in the hands and feet. Additionally, chemotherapy-induced anemia reduces oxygen supply to tissues, which can further contribute to cold sensations.
Infections can sometimes cause an unusual drop in body temperature, making it crucial for patients experiencing persistent chills or cold sensitivity to seek medical attention. If a patient feels excessively cold, they should monitor for other symptoms like fatigue, dizziness, or any signs of infection.
Staying hydrated, dressing in warm layers, maintaining good nutrition, and consulting a doctor for potential underlying issues — such as anemia or infection — can help manage these symptoms effectively.