NITYA Pharmacy

26/08/2025

17/08/2025

In a groundbreaking development, South Korean scientists have discovered a way to reprogram cancer cells back into healthy tissue—without chemotherapy, radiation, or invasive surgery. This innovative approach could transform cancer treatment, shifting the focus from destroying tumors to coaxing them into behaving like normal cells.

Researchers at KAIST achieved this using an advanced AI tool they created called BENEIN, which maps the intricate gene networks inside cancer cells to find the “master switches” driving their harmful behavior. They identified three key genes—MYB, HDAC2, and FOXA2—and found that silencing them simultaneously in colorectal cancer cells didn’t just slow the disease; it triggered the cells to adopt characteristics of healthy intestinal tissue.

In mouse studies, tumors made up of these reprogrammed cells shrank by 70% and closely resembled normal tissue under the microscope. The method holds the promise of far fewer side effects—avoiding the nausea, fatigue, and organ damage often caused by conventional treatments—while potentially lowering healthcare costs and offering patients a gentler alternative.

This marks a philosophical shift in oncology: treating cancer less as an enemy to annihilate and more as misguided cells that can be guided back to health. While further work is needed to develop safe delivery methods and confirm long-term stability, this breakthrough points to a future where cancer therapy could mean restoration rather than destruction.

16/08/2025

A potential revolution in eye care is emerging as researchers develop eye drops that could clear cataracts without surgery — a breakthrough that may transform the lives of millions. Cataracts, the leading cause of vision loss worldwide, have long required surgical removal. Now, scientists at Anglia Ruskin University have created drops containing VP1-001, a compound that reorganizes the protein clumps clouding the eye’s lens, restoring its clarity and allowing light to pass through again.

In mouse trials with a genetic tendency toward cataracts, the results were striking: a single drop of VP1-001 improved lens focusing in 61% of cases, and 46% showed visibly clearer lenses under the microscope. This is the first strong evidence that some cataracts can be treated at their root — no scalpel needed. While the drops aren’t effective for all cataract types and human trials are still to come, the discovery marks a major step toward personalized, non-surgical treatment.

Though not yet available to the public, the potential impact is huge, especially in areas where surgery is scarce. For now, eye protection through good lighting, sunglasses, and regular checkups remains essential. But in the future, restoring vision might be as simple as applying a drop.

Source: PMID: 33724295, PMCID: PMC7980049, Anglia Ruskin University cataract research

09/08/2025

09/08/2025

05/08/2025

15/06/2025

05/06/2025

A new study suggests that vitamin D supplements may help slow biological aging by preserving telomere length—protective caps on the ends of chromosomes that shorten as we age.

Published in The American Journal of Clinical Nutrition, the study found that adults taking vitamin D3 over several years showed significantly less telomere shortening in white blood cells compared to those taking a placebo. This cellular preservation could equate to roughly three fewer years of biological aging.

The data, drawn from the VITAL trial, involved more than 1,000 participants aged 50 and over and included assessments at two- and four-year intervals. While omega-3 fatty acids showed no significant effect, vitamin D appeared to slow telomere loss, particularly in non-obese and non-white participants and those not on cholesterol medication.

Experts caution that this was a post-hoc analysis not originally designed to assess telomere health, and its generalizability is limited due to participant demographics and data gaps. Still, the findings support growing evidence that vitamin D may offer broader benefits beyond bone health—potentially reducing risks of age-related diseases.

Researchers propose that vitamin D might influence enzymes like telomerase or protect DNA from oxidative damage. However, experts warn against excessive supplementation, as high doses can cause kidney damage due to vitamin D’s fat-soluble nature.

If validated by future studies, these findings could inform new guidelines in preventive medicine, emphasizing vitamin D’s role in healthy aging and cellular longevity.

Follow Science Sphere for regular scientific updates! 🧪

RESEARCH PAPER 📄
Haidong Zhu et al., "Vitamin D3 and marine ω-3 fatty acids supplementation and leukocyte telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial", The American Journal of Clinical Nutrition (2025)

02/06/2025

A 6-year-old boy diagnosed with late-stage canc3r, his father regrets after doctors reveal the cause linked to a popular type of beverage

27/05/2025

24/05/2025

21/05/2025