MedExplore Nexus

MedExplore Nexus Dive into the world of medical science with MedExplore Nexus!

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31/01/2024

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#️⃣"" your life's ECG is smooth and flat that means you are not in reality""
16/01/2024

#️⃣"" your life's ECG is smooth and flat that means you are not in reality""

17/12/2023

Pericardial Effusion: is the acute or chronic accumulation of fluid in the pericardial space (between the parietal and the visceral pericardium) and is often associated with a variety of underlying disorders. The fluid can be either bloody (e.g., following aortic dissection) or serous (usually idiopathic). As the pericardium is rather stiff, the capacity of the pericardial space is limited. In chronic effusion, the pericardium can stretch to a certain degree, accommodating slightly more fluid. In the acute setting, however, the added volume quickly exceeds the maximum capacity of the pericardial space. In both cases, the end result is often cardiac tamponade: compression of the heart that can lead to a life-threatening reduction in cardiac output. Pericardial effusion is initially asymptomatic, but cardiac tamponade has a distinct clinical presentation, including hypotension, tachycardia, jugular venous congestion, and pulsus paradoxus. Echocardiography is the most important diagnostic procedure and usually reveals an anechoic pericardial space. Treatment depends on hemodynamic stability: unstable patients require quick pericardial fluid drainage, through either pericardiocentesis or surgery, whereas in stable patients, treatment focuses on the underlying disease.

ACETYLSALICYLIC ACID : also known as aspirin, antiplatelet agent. Mechanism of action: Irreversible COX-1 inhibition →...
16/12/2023

ACETYLSALICYLIC ACID : also known as aspirin, antiplatelet agent.

Mechanism of action:
Irreversible COX-1 inhibition → inhibition of thromboxane (TXA2) synthesis in platelets → inhibition of platelet aggregation (antithrombotic effect)

* Onset of antiplatelet action : within minutes
* Duration of antiplatelet action: 7 to 10 days

Effects :
* Low dose (below 300 mg/day): inhibition of platelet aggregation
* Intermediate dose (300-2400 mg/day): antipyretic and analgesic effect
* High dose (2400-4000 mg/day): antiinflammatory effect

Indication :
* Acute myocardial infarction
* Acute ischemic stroke
* Angina (stable and unstable)
* Management of ASCVD

Adverse effects:
* Dyspepsia
* Gastric ulceration, hemorrhage, perforation
* Increase bleeding time and prothrombin time
* Tinnitus
* Acute kidney injury
* Salicylate poisoning
* Allergic reaction

Contraindications:
* Febrile illness in individuals < 19 years of age
* Acute gout attack

MOYAMOYA DISEASE: A rare cerebrovascular disorder characterized by progressive stenosis and occlusion in the terminal p...
06/12/2023

MOYAMOYA DISEASE: A rare cerebrovascular disorder characterized by progressive stenosis and occlusion in the terminal part of the internal carotid arteries with the compensatory formation of tiny vessels. Manifestations include transient ischemic attacks, strokes, hemorrhage, and seizures.

🧪Laboratory criterias for diagnosis of diabetes mellitus : 1) symptoms of diabetes + Random plasma glucose > 200 mg/dl, ...
22/11/2023

🧪Laboratory criterias for diagnosis of diabetes mellitus :

1) symptoms of diabetes + Random plasma glucose > 200 mg/dl, or
2) 8 hrs fasting plasma glucose > 126 mg/dl, or
3) 2 hrs post (after taking 75mg glucose ) plasma glucose> 200 mg/dl

Note:
* Impaired fasting glucose (IFG) : FBG levels b/w 110 and 125 mg/dl
* Impaired glucose tolerance (IGT) : Post glucose plasma levels b/w 141 and 199 mg/ dl
* Patients with IFG and IGT are not labelled as diabetics but are at risk of developing diabetes and cardiovascular disease.

Symptoms of diabetes :

1) Polyphagia, polydipsia, and polyuria
2) Unexplained weight loss
3) fatigue, Pruritus
4) Poor wound healing
5) Increased susceptibility to infections
6) Calf cramps

🧠 Diabetes mellitus should be suspected in patients with recurrent cellulitis, candidiasis, dermatophyte infections, gangrene, pneumonia (particularly tuberculosis reactivation), influenza, genitourinary infections (UTIs), osteomyelitis, and/or vascular dementia.

🌐 Exciting Medical News! 🏥🔬"Intelligent Stethoscope Detects Peripartum Cardiomyopathy"In a groundbreaking study, Mayo Cl...
22/11/2023

🌐 Exciting Medical News! 🏥🔬

"Intelligent Stethoscope Detects Peripartum Cardiomyopathy"

In a groundbreaking study, Mayo Clinic's Dr. Demilade A. Adedinsewo reveals that using the advanced Eko Duo digital stethoscope, enhanced with artificial intelligence, doubled the detection of peripartum cardiomyopathy in Nigerian obstetric patients. The Screening for Pregnancy Related Heart Failure in Nigeria (SPEC-AI Nigeria) trial showcased remarkable results, unveiling the potential of AI in healthcare.

Peripartum Cardiomyopathy: Cardiomyopathy characterized by the development of idiopathic HFrEF in the months after or before delivery

Stay informed, stay healthy! 🩺💙

21/11/2023

👋 Welcome to a hub of medical wonders and knowledge — MedExplore Nexus! 🚀✨We're thrilled to embark on this journey with you as we delve into the intricate world of medical science. Whether you're a fellow medical student, healthcare professional, or simply fascinated by the marvels of medicine, you've found your space.

🔍 What to Expect:
🧠 Insightful articles on cutting-edge medical research.🎥 Engaging videos unraveling medical mysteries.🌐 Global perspectives on healthcare advancements.🤝 Collaborations with experts in diverse medical fields.📚 Resources to fuel your curiosity and passion for medicine.

💬 Join the Conversation: We believe in the power of community and shared knowledge. Share your thoughts, questions, and experiences in the comments. Let's learn from each other and build a supportive network!

🚀 Get Ready to Explore: Buckle up for a journey through the realms of medical science. Hit that 'Follow' button, turn on notifications, and let the exploration begin!

🤝 Connect with Us: Feel free to reach out with your ideas, collaborations, or simply to say hello. This space is as much yours as it is ours.

Welcome aboard, MedExplorers! 🌟 Let's unravel the mysteries of medicine together.

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