
12/07/2025
Neanderthal Gene Variants Are Linked to Autism Traits in Modern Humans, Study Finds
A new study published in Molecular Psychiatry reveals that certain genetic variants inherited from Neanderthals may influence traits associated with autism spectrum disorder (ASD).
Researchers from Clemson and Loyola Universities analyzed whole-genome data from individuals with autism, their unaffected siblings, and unrelated controls.
They discovered that specific Neanderthal-derived gene snippets appeared more frequently in autistic individuals—not due to a greater overall Neanderthal DNA presence, but because of unique brain-related variants. These variants were linked to stronger visual processing and weaker activity in brain networks tied to social interaction, mirroring some common autistic traits.
The findings offer a surprising evolutionary perspective: ancient genes that may once have enhanced survival in small, perceptually focused Neanderthal communities could still shape modern cognitive styles. These inherited traits—such as heightened attention to detail, visual acuity, and logical planning—may help explain the global presence of autism and shared strengths seen across neurodiverse families. While genetics is only one piece of the puzzle, the study reframes autism as part of humanity’s diverse evolutionary legacy, challenging outdated notions of neurodiversity as merely a disorder rather than a natural variation rooted in our shared past.
learn more https://www.nature.com/articles/s41380-024-02593-7