03/09/2021
Vitrification is a technology that is used in the embryo and egg freezing process so that they
can be stored for later use. It is a technology that has many uses outside of fertility care with
egg and embryo freezing, as it allows something with a crystalline structure to be converted into
something very smooth. When we freeze cells in a lab, the main focus of the process is avoiding ice
crystal formation as the fluid in the cell cools to subzero temperatures. Ice crystals pose 2
significant and deadly problems for cells.
First, an ice crystal is razor sharp and will readily shred any cell membrane.
Second, as water in the cell turns to ice, it expands in volume, rupturing (killing) the cell.
As a result, processes must be developed that allow cells to be frozen while avoiding the formation of ice.
When compared to IVF cycles using fresh eggs and embryos, research suggests that frozen eggs and embryos may increase the likelihood of success. The reason for these increased success rates could be related to the use of medications for ovulation induction.
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