OSHO CLinic Psychiatry & Psychology

16/04/2024

Power and Justice ( Global paradox )

Power is an animalistic behavior, through which humanistic invention “justice” is served. ( biggest lie and root cause of human suffering )
There is no concept of “ justice “ and “ deeds” and their aftermath in animals or any other species. But evolutionary frontal lobe of human brain changed everything and invention of “ justice” emerged.
Animalistic nature of power was smartly used by human race to serve so called “Justice”. Justice is very lucrative and well appreciated term by all of us. Two opposite are made interlinked and whole human race is deluded with synchronicity of both.
Should humans believe in justice that is governed and guided on piles of power?
Why one should wait for justice if it is influenced by power?
Everyday injustice is happening with weak people, employer use power against employees. Politicians , administrators, judiciary, police, all rich, misuse power and favour their favourites with all kind of vested interests
Today I had encounter with one IAS officer and director of very sensitive department. I was saddened to witness that how justice has been crushed by power and shamelessly , Ironically, she has no acceptance or shame that she is tarnishing justice by her misuse of power and her vested interest.
An IAS or IPS or ministers are favourable jobs , not because of their talent for justice but because they pre assumed by people to rich and manipulative and powerful.
This veil has been so invisible that almost all powerful administrators are wilfully control our lives of common people for their own favour-and rewards and no one can dare to question powerful people.
Why justice has been introduced and valued and linked with power so much if it is impossible or not plausible in human race. We all talk about injustice and give strong opinions against it, but we witness it every day life and don’t recognise or deny it.
Why we all common people are deluded
about concept of justice? Why we need power for justice? Power and justice are two opposite ends.
Why we are not made aware about value of power during our bringing up? Why power is not the ultimate goal of life teachings?
Since the origin of human race, Power was the main agenda to survive. With passage of time and evolution , powerful tribes learned more easy and comforting way to maintain and then these tribes introduced the concept of justice. Irony was that, justice term was intended for masses and weak class of people. It was smartest move by powerful human race to cut down their enemies and now the fight was between two powerful people. Rest all were deluded with the concept of justice.
What if our blue print ( DNA) has no concept of justice or not meant for this man made term? Is there any concept or receptors is human brain for justice and its impact? Are we all made hypnotic?
Our whole human history has been deprived from the truth that only power exists and survives.
In end I will quote words from my favourite philosopher “ Fredrick Nietzsche “
“ Ultimate purpose or goal of human life is to seek power” “ Rest all is conspiracy”

“Justice is imposed burden on weak race invented by power and only exists in human race”

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16/02/2024

Not for weak hearted✍🏿

Mystic Pad 🤔of Sir Sigmund Freud; his vision to understand human mind through “ mystic Pad”
Mystic pad of Freud is three layer object, where lower base is of dark resin covered by wax paper and topmost celloloid layer. Base of mystic pad represents the unconscious mind, wax sheet represent conscious awareness of what Stylus( we will discuss in later part) is writing. celluloid layer( perception ) only function as protection to tearing chance of Wax sheet ( consciousness) by stylus. In romantic play of stylus, celluloid and wax sheet is what makes permanent ingrained expression of stylus on dark basin base layer( unconscious). Freud wrote that when stylus in not in use, wax sheet ( consciousness) start fading and impression by stylus disappear. And circle of rewriting and fading goes on.
Stylus is functional aspect of both perception ( first layer) and consciousness ( second layer)

Freud, gave immense importance to base layer where impression are permanent and visible under light or symbolization. He further explained that dark resin base is the infinite “void” or abyss and has intense gravitation to pull desires and to fill the “ cosmic void”.
Dark resin is chimeric in nature and alter its impression in chaotic way. Or just entropy plays in randomness. Ironically this randomness can be altered by consciousness and perception through stylus.
Can fetus feel emotions? or any fear? Or does fetus feel emotions? Is fetus is in absolute bliss(no desire)?
Freud believed and demonstrated absolute blissfullness and hence the infinite void. Freud beautifully explained that prenatal period pure dark resin without other two layers and stylus.
It means without perception and consciousness and hence “ no mind” state.

Modern behavioural science also agreeing to mystic pad concept of Freud but in more refined intellectual, and in more real way.

Our current genome, in amalgamation of billions of genes of our ancestors. This legacy is dark resin of first layer, and possess unique intelligence. Our consciousness is directly influenced by base of mystic pad and perception is epigenetics. Epigenetics is only part that can altered to alter consciousness and even uneven dark resin ( unconscious layer)

We will continue further shortly 🙏

OSHO CLinic Psychiatry & Psychology
Oshoclinicpanchkula.Com
Oshomindcareclinic@gmail.com

DBTDialectical Behavioural Therapy The treatment of all aspects of mental health. Childhood Behavioral Disorders Child psychologist in Panchkula Psychiatric Disorders Drug De-addiction treatment in Panchkula – For Consultation Contact today. Su***de Prevention Helpline Helpline 24/7 Call Now: +91 ...

08/02/2024

Autism Spectrum and Cannabinoids

Autism spectrum disorder (ASD) is a group of heterogeneous neurodevelopmental disorders, commonly characterized by an early-onset impairment in social interactions and communications, accompanied by restricted or repetitive patterns of behavior, language deficits and cognitive impairments. Approximately 50% of ASD children and adolescents demonstrate behavioral difficulties, including aggression, self-injury, tantrums and attention deficit, hyperactivity.

The incidence of ASD is about 1–2.5%(quite alarming)

The endocannabinoid system in ASD

The endocannabinoid system, the endogenous target of cannabis active pharmaceutical ingredients plays an important role in central nervous system development, in synaptic plasticity, and in the response to endogenous and environmental challenges.
Particularly, the ECS has been shown to participate in the regulation of social reward behavior, plausibly by oxytocin-dependent activation of the ECS.

The ECS comprises cannabinoid receptors, endocannabinoids as potentially ligands, and enzymes responsible for the synthesis and degradation of these endocannabinoids.
Two most potent 2-Arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamine (Anandamide, AEA) are the best-studied endocannabinoids. They have different synthesis and degradation conducted by different enzymatic pathways and impart distinct physiological and pathophysiological roles. The ECS involves multiple cannabinoid receptors, the most common being cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2), which are mostly expressed in the central nervous system and throughout the immune system, respectively.
Other receptors include the transient receptor potential (TRP) channels, and the peroxisome proliferator activated receptors (PPAR’s). In addition to their activation by endogenous cannabinoids.

Currently, no established pharmacological treatment for the core symptoms of ASD is available. Some medications were approved by the US (FDA) to treat associated symptoms, including irritability, aggression and behavioral disorders. Commonly used medications include psychotropic drugs (such as atypical antipsychotics), selective serotonin reuptake inhibitors (SSRI’s), stimulants or anxiolytics.

Low dose risperidone and aripiprazole have FDA approval for behavioural issues in ASD.

Cannabis is a multifaceted plant with hundreds of different chemical entities, including cannabinoids, terpenes and flavonoids. Among the cannabinoids, the most abundant in terms of content and studies, are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC, the psychoactive cannabinoid, binds with high affinity to the two ECS main receptors, CB1 and CB2. Common effects of THC include euphoria, altered sensory perception and relaxation. Given its psychoactive potential, THC is rarely used in young ASD patients. CBD has a much wider role, potency and receptor binding properties in a variety of conditions. CBD effects include anticonvulsant, anxiolytic, anti-inflammatory, anti-oxidant and neuroprotective and neuroregulatory functions. CBD interacts with many signaling systems, including TRPV1 (Transient Receptor Potential cation channel subfamily V member 1), TRPV2 (Transient Receptor Potential cation channel subfamily V member 2), adenosine, 5-HT1a (serotonin 1A and PPARγ (Peroxisome proliferator- activated receptor

Studies have pointed to a possible deficiency of the ECS in ASD, which is plausibly involved in ASD. Alterations of the ECS have been demonstrated in several animal models of ASD. In some of these models, activating the ECS reversed the social deficits. Recent studies have demonstrated lower serum levels of AEA, as well as of PEA (N-palmitoylethanolamine) and OEA (N-oleoylethanolamine); two endocannabinoid-like compounds in children with ASD as compared to controls. These may suggest that impaired signaling of AEA (and possibly of their associated compounds) is involved in the pathophysiology of ASD.

Specifically for the case of ASD, CBD may play a role in the regulation of social cognition and behavior via interaction with oxytocin and vasopression signaling at TRPV1 and TRPV2 CBD further acts as an antidepressant and an anxiolytic agent, via 5-HT1a modulation, and most importantly, elevates AEA levels, as a modulator of its degraded enzyme, FAAH (Fatty acid amide hydrolase).

Cannabidiol ( CBD ) already has US FDA approval for resistant seizures in Dravet syndrome, Lenox Gestaut syndrome and tuberous sclerosis complex with significant efficacy. India has recently got approval for CBD use for mentioned indications.
Dosages of CBD in autism are much lower ( 0.2-0.5mg/kg ) than in other indications( 5-15/mg/kg.

Though, we don’t have FDA approval for CBD use in autism but its positive effects are well published as case series and one recent double blind placebo control trial.
Moreover, THC as low dosages along with CBD and other cannabinoids may potentials its efficacy.
The entourage effect of cannabis is well known and might be Midas touch in ASD also.

I personally have seen modest to good results of L- Carnosine in ASD and other neurodevelopment disorders and I am in for use of CBD in ASD

More research and clinical trials might prove more and more use of Cannabis extract in various mental health disorders.

OSHO CLinic Psychiatry & Psychology
Oshomindcareclinic@gmail.com

DBTDialectical Behavioural Therapy The treatment of all aspects of mental health. Childhood Behavioral Disorders Child psychologist in Panchkula Psychiatric Disorders Drug De-addiction treatment in Panchkula – For Consultation Contact today. Su***de Prevention Helpline Helpline 24/7 Call Now: +91 ...

17/05/2023