29/07/2024
Most Chronic Kidney Disease (CKD) patients treated with stem cells typically observe improvements in the following expanses: BUN and creatinine levels regularizing. Better-quality filtration. Balancing salts and minerals.
Chronic Kidney Disease - CKD Symptoms
Many Chronic Kidney Disease (CKD) patients are asymptomatic and usually find it through chance findings from regular screening tests, usually through a routine medical examination or until they become unwell due to advanced CKD.
However, depending on the cause, in a few CKD patients, the symptoms are seen due to impaired kidney function. As CKD progresses, kidney function becomes less effective and uraemic toxins accumulate in the body.
These uraemic toxins not only help in the progression but also influence either directly or indirectly influence biochemical and physiological effects in CKD patients, contributing to immune dysfunction, vascular disease, platelet dysfunction and increased bleeding risk, dysbiosis in the gut (imbalanceβ in the gut microbes), altered drug metabolism. A few of the chronic renal failure symptoms can be seen below:
Pallor (an unhealthy pale appearance) is usually due to anaemia from CKD.
Shortness of breath is due to fluid overload, anaemia, cardiomyopathy etc.
Itching is usually due to uremic toxins and the deregulation of the immune response.
Cramps are typically worse at night due to neuronal irritation caused by biochemical abnormalities in CKD patients.
Cognitive changes are seen in CKD patients, and skills decline at different rates. Language and attention may be particularly affected.
Gastrointestinal symptoms such as anorexia (an eating disorder of obsessing overweight and intake), vomiting, and taste disturbance may occur in advanced CKD patients.
The caretakers may notice uraemic breath in advanced CKD patients due to the breakdown of urea by saliva.
Change in urine output, such as polyuria (more urination) due to impaired tubular concentration, oliguria (small amounts of urine), nocturia (urine during the night), and proteinuria (protein in urine).
Haematuria (blood in urine)
Peripheral oedema (swelling in your lower legs or hands) due to renal sodium retention.