20/08/2025
Agilent ZORBAX Reversed-Phase HPLC Columns.
ZORBAX is one of the most popular high-performance reversed-phase HPLC column families. ZORBAX columns are based on traditional fully porous particles and offer the highest loading capacity and resolution. From Eclipse Plus, Eclipse XDB, StableBond, Bonus-RP and more, the ZORBAX column portfolio offers a wide selection of stationary phases allowing you to fine-tune your selectivity to match your application. Improve resolution by utilizing sub-2 µm particles to maximize system efficiency and confidently scale-up to preparative HPLC and/or easy HPLC method transfer.
Features
Traditional, fully porous particles available in 1.8, 3.5, and 5 µm sizes. With selected products also available in 7 μm particles for preparative HPLC (see Prep LC columns section)
ZORBAX Eclipse Plus columns are the recommended starting point for method development at mid-pH and benefit from the ultimate performance from fully porous silica-based columns
ZORBAX StableBond columns offer the highest stability for low pH applications down to pH 1 while ZORBAX SB-Aq deliver robust, reproducible separations with highly aqueous mobile phases, including 100% water
ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization. These columns are eXtra Densely Bonded (XDB) and double endcapped through a proprietary process to cover as many active silanols as possible. Eclipse XDB columns are available in 1.8, 3.5, 5 and 7 μm particle sizes for high speed, high resolution, analytical and prep scale separations
ZORBAX Extend-C18 columns offer high efficiency and selectivity advantages for basic compounds in for high pH applications up to pH 11.5
ZORBAX Bonus RP columns offer unique selectivity due to an embedded amide linkage in the C14-alkyl chain making them ideal for 100% aqueous mobile phases and for compounds that are not retained on standard reverse phase columns
ZORBAX Rx columns are made from highly pure (>99.995 %) porous silica with a higher carbon load (12%)
ZORBAX Eclipse PAH columns deliver high resolution separation of the 16 polycyclic aromatic hydrocarbons (PAHs) in EPA 610 and have been specifically tested with PAHs for maximum reproducibility