LCGC Bioanalytic Solutions, 105, Champaklal Indl Estate, Nr. Sion tele. exchange, Sion-(E) Mumbai, Sion (2025)

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105, Champaklal Indl Estate, Nr. Sion Tele. Exchange, Sion-(E) Mumbai

01/08/2025

GL Sciences Inertsil C8-3.

The same base silica gel and bonding technology that is used for Inertsil ODS-3 is also employed for Inertsil C8-3. The difference between the two phases is just the length of the hydrocarbon ligands. 10 μm particle size columns are also available to meet the requirement of various pharmacopeia methods. We recommend InertSustain C8 columns for all new method development.

Base Material: 3 Series High Purity Silica Gel

Particle Size: 2 µm, 3 µm, 5 µm, 10 µm

Surface Area: 450 m2/g

Pore Size: 100 Å (10 nm)

Pore Volume: 1.05 mL/g

Functional Group: Octyl

End-capping: Yes

Carbon Loading: 9.0 %

USP Code: L7

pH Range: 2 - 7.5

17/07/2025

GL Sciences Inertsil ODS-HL.

Inertsil ODS-HL employs a highly inert packing material which provides pure hydrophobic interaction between analytes without generating any secondary interaction delivering sharp peaks. High-Density bonding of C18 phase delivers alternative selectivity to conventional C18 columns. Inertsil ODS-HL column is applicable for impurities in pharmaceuticals analyisis.

Base Material : 3 Series High Purity Silica Gel

Pore Size : 1.9 µm, 3 µm, 5 µm, 10 µm

Surface Area : 450 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 1.05 mL/g

Functional Group : Octadecyl

End-capping : Yes

Carbon Loading : 23.0 %

USP Code : L1

pH Range : 2 - 7.5

14/07/2025

GL Sciences InertSphere Sugar-1.

InertSphere Sugar-1 is a suitable anion-exchange column for sugar analysis. It is packed quaternary ammonium group binding polymer. High sensitivity sugar analysis is available using an electrochemical detector. Especially InertSphere Sugar-1 is suitable for Monosaccharide and Disaccharide analysis.

Note) Solvent Bottle with CO2 Trap Cartridge is necessary for analysis to avoid dissolving carbonate ion in the solvent. The Solvent Bottle CO2 Trap Cartridge contains hazardous material which requires special freight handling. Additional charges apply.

07/07/2025

GL Science InertSustain Cyano.

The Most Reliable and Reproducible Cyano Column

In general, the stability and reproducibility of the Cyano phase available in the market are poor. Many batch-to-batch or lot-to-lot reproducibility issues are occurring at many laboratories. The InertSustain Cyano columns were developed to resolve these problems and are designed using the most modern LC column technology available providing them to be extremely inert, stable and reproducible. The InertSustain Cyano columns are highly recommended for all pharmacopeia methods requiring a Cyano phase to be used. (Ex: USP L10)

Benefits

■ Endlessly reproducible from column-to-column and batch-to-batch

■ Highly recommended for all pharmacopeia methods requiring a Cyano phase to be used (Ex: USP L10)

■ Highly inert packing material results in less tailing of peaks for virtually any type of analytes

■ A new selectivity option for method development due to the multiple retention mechanisms

■ Originally shipped in reversed-phase solvents and is ready to use for reversed-phase methods

■ Can be used for both reversed-phase separations as well as normal-phase separations

Base Material : High Purity ES Silica GelParticle Size : 3 µm, 5 µm

Surface Area : 350 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 0.85 mL/g

Functional Group : Cyanopropyl

End-capping : Yes

Carbon Loading : 8.0 %

pH Range : 2 - 7.5

01/07/2025

GL Sciences InertSustain Amide.

InertSustain Amide is a HILIC column that enhances the retention of extremely polar compounds.

This column offers the strongest retentivity among the marketed amide columns through bonding of carbamoyl groups. It achieves superior stability and durability even for water-rich mobile phases.

HILIC phases are particularly useful for compounds that are weakly retained by reversed phase columns such as Melamine and Cyanuric Acid.

As shown below, InertSustain Amide provides stronger retention for such analytes compared to other HILIC brand columns.

Base Material: High Purity ES Silica Gel

Particle Size: 3 µm, 5 µm

Surface Area: 350 m2/g

Pore Size: 100 Å (10 nm）

Pore Volume: 0.85 mL/g

Functional Group: Carbamoyl

End-capping: None

Carbon Loading: 15.0 %

USP Code: L68

pH Range: 2 - 8.5

24/06/2025

GL Science InertSustainSwift C18 HPLC Columns

Increasing Efficiency, Throughput and Productivity InertSustainSwift C18 columns are designed to deliver rapid separations with symmetric peaks to minimize analysis time as much as possible. InertSustainSwift C18 is also ideal for LC-MS and LC-MS/MS methods which offer highly sensitive results and enables MS compatible buffers to be used due to the extremely inert silica gel.

Silica : ES (Evolved Surface) Silica Gel

Particle Size : 1.9 μm, 3 μm, 5 μm

Surface Area : 200 m2/g

Pore Size : 200 Å (20 nm)

Pore Volume : 1.00 mL/g

Bonded Phase : Octadecyl Groups

End-capping : Complete

Carbon Loading : 9.0 %

USP Code : L1

pH Range : 1.0 to 10.0

Benefits

■ Rapid elution of samples in isocratic methods

■ Rapid column equilibration

■ Highly inert packing material results in less tailing of peaks for virtually any type of analytes

■ Deliver extreme sensitivity analysis in LC-MS and LC-MS/MS methods with low column bleed

■ Extreme resistance to low and high pH mobile phases

■ Excellent stability to 100 % aqueous mobile phases

■ Endlessly reproducible from column-to-column and batch-to-batch

20/06/2025

GL Sciences InertSustain AQ-C18

InertSustain AQ-C18 columns are designed to achieve strong retention for highly polar compounds, which is the most challenging goals in developing reversed phase methods. The optimization of bonding of the C18 groups at equal distance to the silica gel enable InertSustain AQ-C18 to offer significant retention for highly polar compounds even under water rich mobile phases.

Specification :

Base Material : High Purity ES Silica Gel

Particle Size : 1.9 µm, 3 µm, 5 µm

Surface Area : 350 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 0.85 mL/g

Functional Group : Octadecyl

End-capping : Yes

Carbon Loading : 13.0 %

USP Code : L1

pH Range : 1 - 10

16/06/2025

GL Sciences Inertsil C8.

Inertsil C8 columns have a pore size of 150 Å and it is recommended for rapid analysis of highly hydrophobic compounds. We recommend InertSustain C8 or Inertsil C8-4 columns for all new method development.

Specification :

Base Material : 2 Series High Purity Silica Gel

Particle Size : 5 µm

Surface Area : 320 m2/g

Pore Size : 150 Å (15 nm)

Pore Volume : 1.20 mL/g

Functional Group : Octyl

End-capping : Yes

Carbon Loading : 10.5 %

USP Code : L7

pH Range : 2 - 7.5

12/06/2025

GL Sciences InertSustain Phenylhexyl.

InertSustain Phenylhexyl columns are bonded with phenylhexyl groups, which employs a phenyl ring with a hexyl (6- carbon) linker and is densely bonded to our newly developed ES silica gel delivering complementary selectivity to straight alkyl-chain columns, but with industry leading inertness, lot-to-lot reproducibility and low back pressure.

Specification :

Base Material : High Purity ES Silica Gel

Particle Size : 3 µm, 5 µm

Surface Area : 350 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 0.85 mL/g

Functional Group : Phenylhexyl

End-capping : Yes

Carbon Loading : 9.0 %

USP Code : L11

pH Range : 1 - 10

09/06/2025

GL Sciences InertSustainSwift C8.

InertSustainSwift C8 is an octyl group (C8) bonded column offering the same extreme inertness to any type of compounds just like InertSustainSwift C18, which is ideal for analyzing low polarity analytes. In addition, the optimized 200 Å pore size silica enables to analyze and retain peptides and oligonucleotides which have a molecular weight from several kDa to several dozen kDa.

Specification :

Base Material : High Purity ES Silica Gel

Particle Size : 1.9 µm, 3 µm, 5 µm

Surface Area : 200 m2/g

Pore Size : 200 Å (20 nm)

Pore Volume : 1.00 mL/g

Functional Group : Octyl

End-capping : Yes

Carbon Loading : 6.0 %

USP Code : L7

pH Range : 1 - 10

04/06/2025

GL Sciences Inertsil NH2

Inertsil NH2 shows far superior stability compared to other brand available aminopropyl columns, as our newly developed "Evolved Surface Silica" is chemically bonded with aminopropyl group. Generally, aminopropyl columns are used for applications that are hard to be separated in a reversed phase mode, such as simultaneous analysis of sugars or vitamin E. However, the shift in retention time has been an issue for a long time. Inertsil NH2 delivers highly reliable reproducibility and stability with accurate qualitative and quantitative results. Furthermore, aminopropyl columns generally cannot be washed by weakly acidic eluent, however Inertsil NH2 was improved and it can be washed by weakly acidic eluent.

Base Material: 3 Series High Purity Silica Gel

Particle size: 3 µm, 5 µm

Surface Area: 450 m2/g

Pore Size: 100 Å (10 nm)

Pore Volume: 1.05 mL/g

Functional Group: Aminopropyl

End-capping: None

Carbon Loading: 8.0 %

USP Code: L8

pH Range: 2 - 7.5

LCGC Bioanalytic Solutions

01/08/2025

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