14/03/2026
What really happens in fascia during treatment?
In this scoping review the authors investigate the therapeutic mechanism of fascial manipulation analyzing eleven studies to hightlingth the fascial manipulation's effects on:
• physiological mechanism
• structural mechanism
• neuromuscular mechanism
In humans, manual therapy triggered a transient local inflammatory response, increasing tissue temperature without activating coagulation or thrombosis risk.
The treatment also reduced unbound water in the deep fascia, supporting pain relief and improved mobility.
Animal studies showed anti-inflammatory effects through cytokine regulation and adenosine receptor involvement, while massage-like stimulation produced opioid-independent analgesia.
Clinically, fascia manipulation was associated with:
✔ pain reduction related to fascial densification
✔ improved proprioception
✔ enhanced reaction time, movement efficiency and motor performance, with effects lasting up to one week
These findings help explain how Fascial Manipulation® influences fascia from a physiological and neuromuscular perspective.
🔬 LINK PUBMED: https://pubmed.ncbi.nlm.nih.gov/40368128/
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🌐 Sito web: fascialmanipulation.com
