Nuclide Notes

Nuclide Notes Nuclear Medicine | Hybrid Imaging | FASNC | FEBNM | CBCCT

☢️ Incidental findings of cystocele and uterine prolapse ☢️ The FDG PET/CT scan shows enlargement of the va**na containi...
21/09/2025

☢️ Incidental findings of cystocele and uterine prolapse ☢️ The FDG PET/CT scan shows enlargement of the va**na containing pr*****ed urinary bladder and uterus.
🗓️ Cystocele and uterine prolapse are two related conditions that affect the pelvic organs, specifically the bladder and uterus. Cystocele, also known as a fallen or pr*****ed bladder, occurs when the supportive tissues between the bladder and va**nal wall weaken or stretch, causing the bladder to bulge into the va**na. This can result in discomfort, urinary symptoms such as frequent urination or leakage, and a feeling of pressure or fullness in the pelvis. Uterine prolapse, on the other hand, happens when the muscles and ligaments supporting the uterus become weak, causing the uterus to descend into the va**nal canal. This condition can lead to symptoms like pelvic heaviness, va**nal protrusion, difficulty with bowel movements, and urinary issues.

☢️ Tibialis posterior tenosynovitis ☢️ Intense linear FDG uptake throughout left tibialis posterior soft-tissue fullness...
19/09/2025

☢️ Tibialis posterior tenosynovitis ☢️ Intense linear FDG uptake throughout left tibialis posterior soft-tissue fullness, extending from the region posterior to the medial malleolus to the tendon’s insertion at the navicular tuberosity. Intense FDG uptake in left sinus tarsi soft tissue fullness.
🗓 Tibialis posterior tenosynovitis is inflammation of the tendon and its synovial sheath as it curves behind the medial malleolus toward the navicular. The malleolar “wrap-around” part acts as a functional enthesis, which means the tendon is compressed against bone, and the adjacent synovial sheath has fibrocartilaginous lining. Inflammation at this pulley therefore behaves like enthesitis, even though it is not a classic bony insertion.

❓All of the following are causes of FALSE POSITIVE focus in parathyroid scan EXCEPT
09/09/2025

❓All of the following are causes of FALSE POSITIVE focus in parathyroid scan EXCEPT

☢️ Pancreatic ductal adenocarcarcinoma ☢️ FAPI PET/CT scan shows intense FAPI avid pancreatic relatively marginated, mas...
08/09/2025

☢️ Pancreatic ductal adenocarcarcinoma ☢️ FAPI PET/CT scan shows intense FAPI avid pancreatic relatively marginated, mass like soft tissue fullness centered at the body/neck with effacement of the normal lobulated architecture. The mass appears heterogeneous with small low density foci suggestive of necrosis, without macroscopic fat or calcifications. There are multiple hepatic poorly defined hypodensities of intense FAPI uptake in both lobes. Retroperitoneal lateral para-aortic and aortocaval lymph nodes of mild to moderate FAPI uptake [SUVmax= 4.4].
🗓 FAPI PET/CT targets fibroblast activation protein expressed by cancer-associated fibroblasts within the desmoplastic stroma of pancreatic ductal adenocarcinoma with high tumor-to-background contrast in the primary tumor and metastases. Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer, arising from the epithelial lining of the pancreatic ducts and characterized by a dense desmoplastic stroma. Clinically it often presents with painless jaundice, weight loss, epigastric/back pain, or new-onset diabetes; common risk factors include smoking, chronic pancreatitis, age, and certain germline mutations.

☢️ Tuberous sclerosis ☢️ on CT quick spotters: Brain with subependymal nodules (coarse calcifications), cortical/subcort...
01/09/2025

☢️ Tuberous sclerosis ☢️ on CT quick spotters: Brain with subependymal nodules (coarse calcifications), cortical/subcortical tubers ± calcification, and SEGA at/near the foramen of Monro; Chest showing diffuse thin-walled cysts of LAM; Kidneys with multiple bilateral angiomyolipomas containing macroscopic fat and renal cysts (watch for acute hemorrhage); Liver/Spleen may show extra-renal AMLs/cysts; Bones with sclerotic enostoses; Heart with classic rhabdomyomas and especially in adults focal intramyocardial macroscopic fat foci.

☢️ Scapula high grade osteosarcoma ☢️ FDG PET/CT scan demonstrates hypermetabolic aggressive periosteal ossification inv...
27/08/2025

☢️ Scapula high grade osteosarcoma ☢️ FDG PET/CT scan demonstrates hypermetabolic aggressive periosteal ossification involving and encircling the upper two thirds of the scapula extending to adjacent soft tissue with underlying cortical erosions. There were also multiple metastatic hypermetabolic sclerotic deposits, bilateral lungs nodules of mild hypermetabolic activity, and supra and infra diaphragmatic lymph nodes. Based on radiological and histopathological findings, the final diagnosis was high grade osteosarcoma.
🗓 High grade sarcoma is a variant of surface osteosarcoma that originates from the periosteum. This type of sarcoma is rare and sporadic with male preference peaking in the 2nd and 3rd decade of life. The most common symptoms are pain and swelling in the affected area, and it is typically diagnosed through a biopsy and imaging tests such as X-rays, MRI, or CT scans. FDG PET/CT scan in osteosarcomas correlates well with histopathological findings, and change in semiquantitative analysis serves as metabolic predictor differentiating responders from non responders after treatment. The reported SN of FDG PET/CT scan is >95% ay initial staging, 85% in assessing recurrence and 95% in assessing for distant metastases.

❓One of the following is not a cause of the finding shown on this thyroid scan
26/08/2025

❓One of the following is not a cause of the finding shown on this thyroid scan

☢️ Cervical disc arthroplasty ☢️ SPECT/CT images shows C5-C6 cervical disc arthroplasty with intense tracer uptake at th...
23/08/2025

☢️ Cervical disc arthroplasty ☢️ SPECT/CT images shows C5-C6 cervical disc arthroplasty with intense tracer uptake at the superior endplate of C6 corresponding to cortical osteolysis, cystic changes and sclerosis along the anterior and posterior endplate. There is a subtle lucent line at the bone-prosthesis interface. There is a zone of osteolysis at the right margin of prosthesis without significant perfusion or delayed tracer uptake. Findings are suggestive of inflammatory osteolysis involving the superior endplate of C6 (probable aseptic osteolysis with interface failure, less likely to indicate infection). Non inflammatory osteolysis at the right margin of prosthesis not showing tracer uptake, suggestive of stress shielding.
🗓️ Bone loss in CDA can be categorized into inflammatory and non inflammatory osteolysis. Non inflammatory bone loss is usually due to stress shielding around the anterior margins and periphery of vertebrae. Inflammatory bone loss is usually pathological and associated with intense tracer uptake, mild to severe osteolysis throughout the vertebral endplates.

☢️ Hepatic angiolipoma ☢️ Incidental finding of a well defined hepatic mass not showing FDG uptake, showing heterogeneou...
19/08/2025

☢️ Hepatic angiolipoma ☢️ Incidental finding of a well defined hepatic mass not showing FDG uptake, showing heterogeneous internal attenuation of fat and soft tissue densities.
🗓 Hepatic angiolipoma is a rare benign tumor that arises in the liver, composed of a combination of blood vessels, smooth muscles and mature fat tissue seen most commonly in the right lobe. Unlike angiolipomas found in other organs, hepatic angiolipomas have been sporadically associated with conditions such as tuberous sclerosis complex and may occur in individuals with no known underlying liver disease. Clinical presentation is usually incidental, but patients may present with acute abdominal pain if there is intralesional or peritoneal bleeding. In contrast enhanced CT the lesion shows significant internal and peripheral enhancement in the arterial phase and hypoattenuating in portovenous phase.

❓Which of the following statements is FALSE?
18/08/2025

❓Which of the following statements is FALSE?

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