11/01/2026
https://www.bmj.com/content/392/bmj-2025-085304
Obesity Is Not a Software Bug You Can Fix with an App.
In metabolic pharmacology, one critically important dimension is almost entirely ignored:
a human being is not just a body.
A human is a layered, complex system.
First, there is the biological, cellular, carbon-based body. Then there is the mind, which itself has two distinct layers:
- the conscious mind — our perceptions, sensations, cravings, and decisions
- the subconscious mind — the hidden software that regulates how those perceptions and desires arise in the first place
Most modern interventions focus exclusively on the surface layer.
The Smartphone Analogy We Keep Ignoring.
If we compare a human being to a smartphone, we quickly realize that we have not invented anything fundamentally new — we have merely mirrored ourselves.
The hardware (processor, sensors, screen, circuits) corresponds to the human body.
The apps we consciously install and use are equivalent to the conscious mind.
And beneath all of this lies the operating system — installed by the developer, mostly hidden, rarely understood, and almost never modified by the average user.
Even when a user accesses the operating system, very few know how to truly optimize it. That domain is reserved for developer settings.
The subconscious mind is exactly that operating system.
Weight-Loss Drugs: App Updates, Not System Changes.
Now let us return to weight-loss medications.
Nearly all currently available pharmacological agents function as app updates.
They influence appetite, satiety, and reward signaling — all features of the conscious sensory mind.
They create an artificial caloric deficit, with some secondary metabolic effects.
That is all.
Once the medication is discontinued, weight regain is not a possibility — it is an expectation.
The operating system remains untouched.
Why the Obesity Pandemic Did Not Exist Before?
The global obesity epidemic did not emerge randomly. It began in the mid to late 1980s.
Following World War II, food scarcity dominated life for decades. Post-war generations — particularly baby boomers and, to a lesser extent, Generation X — were raised in a scarcity paradigm:
- food was monotonous
- portions were small
- calories were dense but limited
- daily intake was routinely insufficient by modern standards
In other words, chronic caloric deficiency was normal.
To illustrate this, I reverse-engineered the diet of my grandfather.
He was a carpenter, lived in a small village, and performed heavy physical labor until late in life.
Breakfast: two raw eggs, a large cup of fresh or fermented milk, rye bread
Lunch: naturally cured fatty pork or lamb, two boiled eggs, rye bread, green onions, garlic, seasonal vegetables or fermented foods
Dinner: a bowl of borsch (Ukrainian veggies and fatty meat soup) or buckwheat milk soup. Meat avoided during religious fasts.
This diet remained remarkably consistent with some variations throughout his life. Only minor variations during holidays and social events.
When I calculated his intake, it averaged 1,500–1,700 kilocalories per day.
Based on his body composition and activity level, his estimated daily requirement would have been 3,500–3,700 kilocalories.
And yet:
he drank 300–500 ml of homemade vodka daily,
he smoked to***co from early childhood,
he was never hospitalized,
he never took medication,
he never saw a doctor — except me, after I became one.
He died at 76 years of age, not from disease, but from a road accident.
This is not nostalgia. This is ancestral nutrition, encoded in our genes.
The Only Sustainable Way Forward.
In my view, ancestral nutrition — adapted to modern life — is the only sustainable solution to the obesity pandemic.
Medications such as Ozempic and its a**logues do not address this. They tweak the apps. They do not rewrite the operating system.
And pharmacology offers no real mechanism to reprogram the subconscious.
My prediction is simple:
either these medications will fade within a few years, or they will become lifelong dependencies.
A Personal Case Study.
In November 2025, I stepped onto the scale in my office.
112 kg.
That moment was not just a shock — it was a subconscious event. Stress, fear, and clarity converged.
Something fundamental shifted.
Yesterday, I weighed 91 kg.
That is 21 kg lost.
My height is 187 cm, and I am steadily approaching my ideal range of 82–84 kg, which I expect to reach by mid-March.
But reaching a number is irrelevant.
What matters is that the operating system has been rewritten.
I redesigned my own version of ancestral nutrition. I discarded the modern obsession with basal metabolic rate (BMR) — keeping it only as a rough reference, and then dividing it by two.
Final Thought
The real challenge is not losing weight.
It is preventing the subconscious from reverting to its old code.
And perhaps one day, we will see a time when Big Pharma is not merely questioned — but held accountable by Homo sapiens, the wise human, not the manipulated consumer.
That, to me, would mark true progress.
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