TOMOCUBE

TOMOCUBE See your samples like never before with Tomocube’s revolutionary label-free, live cell Holotomography

Established in 2016, Tomocube is dedicated to delivering products that enhance biological and medical research via novel optical solutions that can assist scientists and clinicians in understanding, diagnosing, and treating human diseases. Holotomography (HT) technology provides label-free 4D quantitative imaging for analyzing cells and tissues. The details of live cell dynamics, subcellular organ

elles, and tissue structures can be seen without preparation including fixation, transfection, or staining. Image data acquisition is supported by AI-driven data analysis software for phenotypic analysis using cellular and sub-cellular segmentation. For more on our products and research, e-mail us on info@tomocube.com or visit us at www.tomocube.com

We'll be at   next week — find us at 𝗕𝗼𝗼𝘁𝗵 𝟵𝟴, BEXCO Convention Hall, Busan, May 27–29.Come by for a 𝗹𝗶𝘃𝗲 𝗱𝗲𝗺𝗼.   lets y...
19/05/2026

We'll be at next week — find us at 𝗕𝗼𝗼𝘁𝗵 𝟵𝟴, BEXCO Convention Hall, Busan, May 27–29.

Come by for a 𝗹𝗶𝘃𝗲 𝗱𝗲𝗺𝗼. lets you image live cells in 3D without staining or phototoxicity — organelle dynamics, dry mass, intracellular structure, all tracked quantitatively over time.

On May 28, we're also presenting a poster on using lipid droplets as intrinsic probes to measure cytoplasmic viscosity. Label-free, naturally.

📅 Exhibit: May 27–29 · Booth 98
🗓 Poster: May 28 · 12:20–13:50 ·

Great news to share: a paper we've been recommending to researchers for the past two year just proved we weren't the onl...
18/05/2026

Great news to share: a paper we've been recommending to researchers for the past two year just proved we weren't the only ones paying attention.

Dr. Francesca Brero's work on label-free 3D imaging of fibroblast-to-myofibroblast transition has ranked in the top 10% most-viewed papers in Microscopy Research and Technique for 2024. Well deserved.

The science speaks for itself. Fibroblasts turning into myofibroblasts drive tissue repair — but also fibrosis when things go wrong. Watching that transition happen in real time, without labels, tracking cell volume, dry mass, and organelle changes as they unfold — that's the kind of data that changes how you think about the problem.

Congratulations to the team. On to the next one.

🔗 https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jemt.24648

Holotomographic microscopy was employed for the first time to detect morphological features of living unlabeled fibroblasts and myofibroblasts turning out as a valid approach. It provided quantitativ...

Day 1 at at ASPIRE 2026 is a wrap.The booth B42 was busy from the start. Researchers stopped to photograph the screens, ...
08/05/2026

Day 1 at at ASPIRE 2026 is a wrap.

The booth B42 was busy from the start. Researchers stopped to photograph the screens, groups huddled around the oocyte data, and the conversations kept going.

lets you image living in 3D — no stains, no markers — and the cells stay viable afterward. That's what makes it relevant for IVF research: image first, then take the same sample to culture or fertilization.

We're here for Day 2. If you're at the congress and haven't stopped by yet — Booth , Tomocube.

Two things surprise most people the first time they see holotomography data of 𝗼𝗼𝗰𝘆𝘁𝗲𝘀 and 𝗲𝗺𝗯𝗿𝘆𝗼𝘀: the imaging is fully...
30/04/2026

Two things surprise most people the first time they see holotomography data of 𝗼𝗼𝗰𝘆𝘁𝗲𝘀 and 𝗲𝗺𝗯𝗿𝘆𝗼𝘀: the imaging is fully label-free (no stains, no fluorescent markers), and the cells stay viable afterward.

That second part matters for IVF research. Image an oocyte, then take the same sample to culture or fertilization.

Tomocube will be at 2026, the 15th Congress of the Asia Pacific Initiative on Reproduction, in Beijing next week. You'll find us at Booth .

Stop by to see the imaging in action, talk through your research questions with our team, or discuss a research collaboration.

27/04/2026

What does drug response look like inside a cancer organoid?

Researchers at the National Cancer Center, Korea, used Tomocube to find out by tracking how Patient-Derived Organoids (PDOs) from 8 cancer types respond to treatments in real time, without any labels.

The result: richer morphological data and faster insights. This is what precision medicine research looks like when the imaging keeps up with the science.

▶️ See it in action.

Gut microbiome → antitumor immunity → endometrial cancer survival. A recent study in Microbiome maps the pathway using m...
24/04/2026

Gut microbiome → antitumor immunity → endometrial cancer survival. A recent study in Microbiome maps the pathway using metatranscriptomics, transcriptomics, and metabolomics.

Bacillus megaterium KCTC 3007, a microbe tied to better patient outcomes, produces TMA. The body converts it to TMAO. TMAO triggers type I interferon signaling and expands CD8+ T cells.

The cellular evidence came from the Tomocube HT-X1. No labels, no fluorescent dyes — just immune cells and tumor cells imaged live. In the treated group, PBMCs attached to cancer cells at a noticeably higher rate. You can watch it happen.

It's a good example of where label-free live imaging fills a gap: watching the interaction happen, rather than inferring it from endpoint assays.

Our sincere congratulations to the teams at Seoul National University Hospital and GIST.

Explore the study and watch the full timelapse videos here:

🔗 https://link.springer.com/article/10.1186/s40168-026-02373-1

Background Endometrial cancer (ECa) is one of the most common gynecologic malignancies, with limited therapeutic responses in metastatic or recurrent cases. The bacterial microbiota has emerged as a key modulator of carcinogenesis and antitumor immunity. However, the role of endometrial microbiota i...

🇨🇳 𝗔 𝗡𝗲𝘄 𝗖𝗵𝗮𝗽𝘁𝗲𝗿 𝗳𝗼𝗿 𝗧𝗼𝗺𝗼𝗰𝘂𝗯𝗲 𝗶𝗻 𝗖𝗵𝗶𝗻𝗮We are thrilled to announce that He Tong is joining Tomocube as our new Sales Dire...
20/04/2026

🇨🇳 𝗔 𝗡𝗲𝘄 𝗖𝗵𝗮𝗽𝘁𝗲𝗿 𝗳𝗼𝗿 𝗧𝗼𝗺𝗼𝗰𝘂𝗯𝗲 𝗶𝗻 𝗖𝗵𝗶𝗻𝗮

We are thrilled to announce that He Tong is joining Tomocube as our new Sales Director for China — a strategic milestone in our mission to bring holotomography and label-free 3D live-cell imaging to one of the fastest-moving life sciences markets in the world.

He Tong brings over 25 years of experience in biomedical imaging, with a career spanning PerkinElmer, GE Healthcare, and Sartorius. His deep expertise in cell imaging technologies and his understanding of China’s academic and biopharma landscapes make him well-suited to lead our growth in the region.

In his own words: “Holotomography technology holds significant application potential, spanning from cells and organoids to in vivo imaging — with broad prospects across basic research, pharmaceutical R&D, and clinical diagnostics.”

📈 With 2026 marking the first year of China’s new Five-Year Plan and investment in life sciences accelerating, the timing couldn’t be better. He Tong will focus on expanding Tomocube’s reach into central and western China, deepening partnerships with academic institutions, and building the foundation for long-term growth across Greater China.

Please join us in warmly welcoming He Tong to the Tomocube team! 🎉

👉 Read the full announcement: https://tomocube.com/tomocube/news/110

Imaging live cancer cells with less staining or no fixation changes what you can actually measure — and what questions y...
13/04/2026

Imaging live cancer cells with less staining or no fixation changes what you can actually measure — and what questions you can ask.

At AACR 2026 in San Diego (April 17–22), our team will be at Booth #1345 to walk through how holotomography works in practice: label-free, quantitative, and compatible with live-cell time-lapse workflows.

We're also inviting you to check out poster works from the KAIST BMOL Lab — applications developed in collaboration with Tomocube, covering virtual H&E in thick tissues, organoid imaging with generative AI, renal pathology, and label-free pharmacodynamic readouts.

All sessions on April 20–21.

If you're working with thick tissue sections, organoids, or drug response assays and want to cut staining out of the equation, come find us at Booth #1345. We're happy to get into the specifics.

This week, we had the pleasure of welcoming Prof. Francisco Javier Nualart Santander and the team from Universidad de Co...
08/04/2026

This week, we had the pleasure of welcoming Prof. Francisco Javier Nualart Santander and the team from Universidad de Concepción to Tomocube HQ as they deepened their journey with holotomography and explored new possibilities with TomoAnalysis.

Judging by the photo, it’s safe to say the trip was productive and very well enjoyed 😄.

A special highlight of the visit was a customer seminar led by Dr. Luciano, where he shared his team’s experience and research progress with the HT-X1™ Plus. What made his presentation especially memorable was not only the science, but the passion behind it — a true reflection of the curiosity, persistence, and excitement that drive meaningful discovery.

Researchers like Dr. Luciano remind us that behind every great application is a person who believed in the potential of the technology and kept pushing forward. We feel incredibly lucky to have users like his team in the Tomocube community.

Thank you again to the Universidad de Concepción team for visiting us — and for bringing both great science and great energy to Tomocube HQ!

Seeing is just the beginning.The real power of label-free 3D   isn't just the images — it's what you can measure from th...
06/04/2026

Seeing is just the beginning.

The real power of label-free 3D isn't just the images — it's what you can measure from them.

Join us at the Annual Meeting of CSCB 2026 in Hefei, China (April 8–12) and explore the HT-X1™ series at Booth . Our team will be there to talk about holotomography and how it's transforming cell biology — from observation to quantitative analysis.

Let's talk science. 🧬
📍 Booth | Hefei, Anhui Province | April 8–12, 2026

We’re pleased to welcome a research team from the Universidad de Concepción (Chile) to our HQ in Daejeon, led by 𝗣𝗿𝗼𝗳. 𝗙...
03/04/2026

We’re pleased to welcome a research team from the Universidad de Concepción (Chile) to our HQ in Daejeon, led by 𝗣𝗿𝗼𝗳. 𝗙𝗿𝗮𝗻𝗰𝗶𝘀𝗰𝗼 𝗝𝗮𝘃𝗶𝗲𝗿 𝗡𝘂𝗮𝗹𝗮𝗿𝘁 𝗦𝗮𝗻𝘁𝗮𝗻𝗱𝗲𝗿.

As part of their visit, 𝗗𝗿. 𝗟𝘂𝗰𝗶𝗮𝗻𝗼, who has been actively using the HT-X1 Plus system in their lab, will lead a customer seminar to share their experience and research progress.

Since the system was installed just a few months ago, the team has already explored a wide range of applications—from cancer biology to stem cell research—while building collaborations across local and international partners.

This visit represents more than a single seminar—it reflects how new imaging technologies are adopted and developed through close collaboration, shared expertise, and growing research networks across regions.

📅 April 7 | 10:30–11:30 AM
📍 Tomocube HQ, Daejeon
✍️ Join us: https://shorturl.at/BjhLv

We look forward to welcoming the team and continuing to build strong, meaningful connections within the global research community.

Address

대전광역시 유성구 신성로 155 4층 (주)토모큐브
Daejeon
34109

Opening Hours

Monday 09:00 - 18:00
Tuesday 09:00 - 18:00
Wednesday 09:00 - 18:00
Thursday 09:00 - 18:00
Friday 09:00 - 18:00

Telephone

+82-42-863-1100

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