
24/09/2025
Dr. Nabil Fakih is recognized as an international expert in vascular occlusion complication after filler in acute phase. He has published several guides and protocols on the management of filler complications and is also the co-founder of the app ➡️fillerrescue.com : a tool designed to assist clinicians worldwide in promptly addressing complications.
Dr. Nabil Fakih’s research and leadership of a team of colleagues in developing the 2025 guideline resulted in the following key findings. I recommend reading the full article, as it is a master research. Additionally including the FOEM2 new grading.
Prompt and effective management of vascular occlusion is critical to prevent irreversible tissue damage. A systematic review of 96 PubMed articles was conducted to create a modern action guide, excluding ocular cases, and focusing on current angiosome-based concepts and advanced interventional radiology strategies.
🔹 Early recognition is essential – Pain and skin color changes remain the most prevalent early warning signs.
🔹 Time-dependent outcome – Intervention within 4–6 hours can reverse ischemia in up to 80% of cases.
🔹 High-dose Hyaluronidase (1500 IU every 15–20 min) remains the gold standard; ultrasound guidance reduces the dose required up to tenfold.
🔹 Adjunct therapies – Antiplatelets reduce platelet aggregation, corticosteroids mitigate inflammation, vasodilators aid perfusion, and hyperbaric oxygen therapy enhances tissue oxygenation.
🔹 Structured protocols – The FOEM2 score and ischemic staging provide a framework for precise, evidence-based treatment decisions.
✅ Conclusion: Timely diagnosis, rapid intervention, and adherence to structured, evidence-based protocols are vital to improve patient outcomes. Establishing standardized guidelines will further elevate patient safety and treatment efficacy in aesthetic medicine.
💥 If any patient requires urgent assistance for a vascular occlusion anywhere in Spain, we are ready to help: +34 603 888 888 💥