The Biochemistry, Biology and Pathology of MAP Kinases II

27/08/2024

https://link.springer.com/collections/ebjfjdbjhb

Cancer is a group of diseases, which are the leading cause of death worldwide. Treatment of cancer have been dramatically revolutionised by targeted therapies ...

19/04/2024

https://www.mdpi.com/2072-6694/16/8/1555

The protein kinases are a large family of enzymes which catalyze protein phosphorylation at certain amino acids [...]

31/08/2023

Due to the success of the first volume on “Kinases in Cancer and Other Diseases”, we are glad to announce that the
second volume of this Topic is opening for submission now.
Topic: Kinases in Cancer and Other Diseases, 2nd Edition
Deadline for manuscript submissions: 31 December 2024
Particapting journals: Cells (SCI, IF 6.0); IJMS (SCI, IF 5.6); Biomolecules (SCI, IF 5.5); Cancers (SCI, IF 5.2);
Pharmaceuticals (SCI, IF 4.6); Biology (SCI, IF 4.2)
Website:

MDPI is a publisher of peer-reviewed, open access journals since its establishment in 1996.

11/07/2019

https://www.mdpi.com/2072-6694/11/7/972/htm

Antitumor drug resistance remains a major challenge in cancer chemotherapy. Here we investigated the mechanism of acquired resistance to a novel anticancer agent RH1 designed to be activated in cancer cells by the NQO1 enzyme. Data show that in some cancer cells RH1 may act in an NQO1-independent wa...

24/12/2018

https://www.mdpi.com/2072-6694/11/1/17/htm

Glioma is the most aggressive brain tumor of the central nervous system. The ability of glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained proliferation, and heterogeneity contribute to an overall survival of approximately 15 months for most patients with hig...

28/04/2017

http://www.mdpi.com/2072-6694/9/5/42 and http://www.mdpi.com/2072-6694/9/5/42/htm

Pancreatic cancer is a disease that has a very high fatality rate and one of the highest mortality ratios among all major cancers, remaining the fourth leading cause of cancer-related deaths in developed countries. The major treatment of pancreatic cancer is surgery; however, only 15–20% of patients...

10/01/2017

http://link.springer.com/article/10.1007%2Fs12032-016-0879-9

Cancers are the group of diseases, which arise because of the uncontrolled behavior of some of the genes in our cells. There are possibilities of gene amplifications, overexpressions, deletions and ot

03/11/2016

http://link.springer.com/article/10.1007%2Fs12032-016-0853-6

Pancreatic cancer is one of the worst prognoses of all malignancies. More than 40,000 deaths a year from this disease are observed in European Union alone. The only possibly curative treatment of panc

23/04/2016

http://benthamscience.com/journal/abstracts.php?journalID=cp&articleID=141228

03/04/2016

http://link.springer.com/article/10.1007%2Fs12032-016-0758-4

Inhibitors that impact function of kinases are valuable both for the biological research as well as therapy of kinase-associated diseases, such as different cancers. There are quite a number of inhibitors, which are quite specific for certain kinases and several of them are either already approved f…

06/03/2016

http://link.springer.com/article/10.1007/s00432-016-2136-1

Compounds that affect enzymatic function of kinases are valuable for the understanding of the complex biochemical processes in cells. Aurora kinases (AURKs) play a key role in the control of the mitosis. These kinases are frequently deregulated in different human cancers: overexpression, amplificati…

29/12/2015

http://www.pagepressjournals.org/index.php/mk/article/view/5700