29/05/2025
🧠🦠 The gut microbiota - our "virtual organ" -has emerged as a central player in human health.
🎯 Over the past decades, research has revealed the gut microbiota’s vital role in both physiological and pathological processes. It acts like a virtual organ, influencing immunity, metabolism, and even brain function. We've come to understand multiple communication pathways - the gut-brain, gut-liver, gut-lung axes, and beyond. 🦠
👉 Among these, the gut–liver axis is especially significant. The gut and liver are deeply interconnected, constantly communicating through bidirectional signaling pathways involving metabolites, immune cells, and the portal circulation.
That’s why we’re thrilled 🎆 to share our latest review article, just published in Microorganisms:
📘 “Gut Microbiota and the Gut–Liver Axis in Liver Disease: From Chronic Viral Hepatitis to Cirrhosis, Hepatocellular Carcinoma, and Microbiome-Based Therapies”
🧬 In this paper, we explore how gut dysbiosis contributes to the progression of liver disease and discuss future microbiome-based therapeutic strategies.
🆓 The article is open-access and freely available here: https://www.mdpi.com/2076-2607/13/5/1053
Chronic viral hepatitis B and C remain major global health challenges, contributing significantly to liver-related morbidity and mortality. Despite antiviral therapies and vaccines for HBV, progression to cirrhosis and hepatocellular carcinoma remains common. For HCV, the lack of a vaccine and high....