31/10/2025
Clove Bud Oil & Cancer Research
Researchers are discovering that eugenol—the main compound in clove essential oil (Syzygium aromaticum)—has shown promising anticancer activity in early lab studies.
In one study, scientists found that eugenol helped prevent the development of skin cancer in lab models by reducing inflammation (lowering levels of cytokines like IL-6 and TNF-α) and by boosting the body’s antioxidant defenses. These effects seem to protect cells from oxidative stress, one of the key drivers of cancer formation (Barboza et al., 2018).
Other studies have looked at eugenol’s effects on cervical and breast cancer cells, showing that it can slow cancer cell growth and even enhance the effects of chemotherapy drugs such as gemcitabine and cisplatin—potentially reducing their side effects.
Researchers believe this happens because eugenol helps the body’s natural “cell cleanup” processes (like apoptosis) work more efficiently and blocks NF-κB, a signaling pathway that drives inflammation and tumor growth.
While these studies are still in early stages and mostly limited to lab and animal research, they point toward eugenol as a promising natural compound for future cancer research—one that may complement conventional treatments or help scientists design gentler, more effective therapies.
This research is exciting, but it’s important to remember that lab studies often use much higher concentrations of clove bud oil than are safe in aromatherapy, or apply it in ways we can’t (like directly to cancer cells in test tubes). Clove bud oil isn’t a replacement for medical treatment, but it can still offer gentle support for wellness, balance, and prevention as part of a holistic lifestyle.
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Safety Notes: Because eugenol is a phenol, clove bud oil can easily irritate the skin or mucous membranes. Always dilute it well in a carrier oil before topical application, typically at no more than 0.5% for general applications. That’s about 2–3 drops per 1 fl oz (30 ml) of carrier. We prefer to avoid using this oil for children under 10, or any person with sensitive skin. Avoid if you have a clotting disorder, are taking an anticoagulant drug, and after surgery. Avoid if you have impaired liver function.
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REF
Barboza, J. N., da Silva Maia Bezerra Filho, C., Silva, R. O., Medeiros, J., & de Sousa, D. P. (2018). An Overview on the Anti-inflammatory Potential and Antioxidant Profile of Eugenol. Oxidative medicine and cellular longevity, 2018, 3957262.
