10/10/2024
Cesar Delgado
Juan Zambrano Ruiz
A 13-year-old boy presented with recurrent fever and abdominal pain for 8 months, followed by a generalised seizure and persistent melaena. Significant findings on examination included severe thinness (BMI-for-age –5·2 standard deviation score), pallor, generalised muscle tenderness, and stage 2 hypertension (blood pressure 136/110 mm Hg).
Investigations identified normocytic normochromic anaemia (haemoglobin 85 g/L), acute kidney injury (serum creatinine 353·6 μmol/L), and elevated inflammatory markers (serum ferritin 3312 pmol/L, serum C-reactive protein 146 mg/L, and erythrocyte sedimentation rate 50 mm/h). Urinalysis revealed proteinuria (2+ on dipstick) and haematuria (4–5 red blood cells per high power field). Serum antinuclear and antineutrophil cytoplasmic antibodies were negative and C3 and C4 complement protein concentrations were normal.
A CT scan with angiography, performed for persistent gastrointestinal tract bleeding, is shown in the image. What is the likely diagnosis? Try our latest Clinical Picture quiz to find out more ▶️ https://hubs.li/Q02Rv-Z70