30/12/2024
WE REPLENISH AT NIGHT
Endogenous melatonin levels peak during the darkest periods of the night, typically 2-4 AM. In addition, at that same time, oxidative stress enzymes, like superoxide dismutase, catalase, glutathione reductase, and even glutathione, are also at their peak. Nighttime, when we are to be sleeping, is our body’s restoration time.
When we miss out on sleep, we miss an opportunity for clearing and cleaning up from the light-filled oxidative bursts of metabolic activity during the day.
Reference: Budkowska M, Cecerska-Heryć E, Marcinowska Z, Siennicka A, Dołęgowska B. The Influence of Circadian Rhythm on the Activity of Oxidative Stress Enzymes. Int J Mol Sci. 2022 Nov 17;23(22):14275. doi: 10.3390/ijms232214275. PMID: 36430753.