06/10/2025                                                                            
                                    
                                                                            
                                            Los ganadores de    de medicina / fisiología de este  #2025 son Mary E. Brunkow, Fred Ramsdell y Shimon Sakaguchi por sus trabajos sobre la tolerancia inmunológica periférica.
Estos científicos identificaron a las células T reguladoras (T reg) las cuales previenen que el sistema inmunológico ataque al mismo cuerpo y evite enfermedades auto inmunes.
En el terreno de la   estás células han cobrado relevancia como parte del micro ambiente tumoral y su probable implicación en la progresión del                                          
                                    
                                                                        
                                        BREAKING NEWS
The Nobel Assembly at Karolinska Institutet has decided to award the 2025 Nobel Prize in Physiology or Medicine to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
This year’s medicine laureates have discovered how the immune system is kept in check. The body’s powerful immune system must be regulated, or it may attack our own organs. Brunkow, Ramsdell and Sakaguchi have been awarded this year’s medicine prize for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.
The laureates identified the immune system’s security guards, regulatory T cells, which prevent immune cells from attacking our own body.
The laureates’ discoveries launched the field of peripheral tolerance, spurring the development of medical treatments for cancer and autoimmune diseases. This may also lead to more successful transplantations. Several of these treatments are now undergoing clinical trials.
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