Dr. Fabían García Santín

Dr. Fabían García Santín Especialista en Medicina Integrada

Manejo Médico Integral en Enfermedades crónico degenerativas

04/01/2026

Peripheral neuropathy, defined as damage to the peripheral nerves, affects approximately 1% of adults worldwide.

This Review summarizes the pathophysiology, clinical presentation, diagnosis, and treatment of length-dependent peripheral neuropathy.

https://ja.ma/497QqF6

04/01/2026

Individuals with treated with stimulants have a nonnegligible risk of developing psychosis or bipolar disorder, with a higher risk associated with amphetamines compared to methylphenidate.

https://ja.ma/44TpPsU

04/01/2026

consistently lowered hospitalization rates and hospital days in high-risk adults with and cardiovascular disease, with effects observed across clinical subgroups. https://ja.ma/4aJHtTQ

04/01/2026

Sarcomas comprise a heterogeneous group of malignant neoplasms that include genomically simple and genomically complex subtypes. This consensus provides guidelines for efficient, rational use of next-generation sequencing in their clinical management.

https://ja.ma/3MWrtUF

04/01/2026

and effectively target and GIP receptors for obesity treatment, with future therapies exploring further receptor targeting for improved outcomes.

https://ja.ma/45Dk5Um

04/01/2026

In patients with ischemic stroke and concurrent nonvalvular atrial fibrillation and ASCVD, adding an antiplatelet agent to anticoagulant therapy offered no net clinical benefit over anticoagulant monotherapy.

https://ja.ma/3YjxwF8

04/01/2026

Ocular toxic effects including keratopathy, blurred vision, cataract progression, and uveitis were common but generally reversible during mirvetuximab soravtansine therapy for FRα-positive gynecologic cancers. https://ja.ma/4biDCgz

04/01/2026

is a common disease among older adults that weakens bones and increases the likelihood of fractures.

This JAMA Patient Page describes osteoporosis risk factors, symptoms, screening, diagnosis, and treatment.

https://ja.ma/492OHAY

04/01/2026

This Review highlights that difficult cholecystectomies are associated with distinct patient, disease, and imaging factors, and emphasizes the need for careful assessment, advanced imaging, and adaptable surgical strategies to prevent serious injuries.

https://ja.ma/4qdgswY

04/01/2026

Clinicians can enhance patient understanding by using numerical data instead of verbal probabilities, consistent denominators, absolute risk comparisons, and clear context for unfamiliar data types.

https://ja.ma/3Ncylgt

02/01/2026

CHA₂DS₂-VA (ACTUALIZADO)

📌 Evalúa riesgo tromboembólico en fibrilación auricular no valvular.

C = Insuficiencia cardiaca / FEVI ≤40% → 1️⃣
H = Hipertensión arterial → 1️⃣
A₂ = Edad ≥75 años → 2️⃣
D = Diabetes mellitus → 1️⃣
S₂ = EVC / AIT / tromboembolismo previo → 2️⃣
V = Enfermedad vascular (IAM, EAP, placa aórtica) → 1️⃣
A = Edad 65–74 años → 1️⃣

🚫 S**o femenino: ya NO puntúa de forma independiente.

🔢 Puntaje máximo: 8

🩸 Interpretación actual:

0 puntos → No anticoagulación

1 punto → Considerar anticoagulación según contexto.

≥ 2 puntos → Iniciar anticoagulación.

💊 Tratamiento de elección:

DOACs (apixabán, rivaroxabán, dabigatrán)

🚨Warfarina solo en FA valvular.

Perla ENARM:

CHA₂DS₂-VASc indica cuándo anticoagular; HAS-BLED solo estima riesgo de sangrado.

02/01/2026

In a phase 3 trial, toripalimab improved progression-free survival over dacarbazine as first-line treatment in advanced predominantly of acral subtype, with an acceptable safety profile. https://ja.ma/4qxzJsq

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Notificaciones

Sé el primero en enterarse y déjanos enviarle un correo electrónico cuando Dr. Fabían García Santín publique noticias y promociones. Su dirección de correo electrónico no se utilizará para ningún otro fin, y puede darse de baja en cualquier momento.

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