Mexicanna CBD Tepic

19/12/2022

https://www.facebook.com/1666575596948833/posts/3360995417506834/?mibextid=Nif5oz

Pharmacological agents limiting secondary tissue loss and improving functional outcomes after stroke are still limited. Cannabidiol (CBD), the major non-psychoactive component of Cannabis sativa, has been proposed as a neuroprotective agent against experimental cerebral ischemia. The effects of CBD....

01/12/2022

https://dailycbd.com/es/cancer-perros/

El cáncer es común en los perros. Aprenda a encontrar los mejores aceites de CBD para perros con cáncer, cómo utilizarlos y qué esperar.

17/10/2022

Medical cannabis is usually well tolerated by older adults.

"In an observational study with 201 older adults with 65 years of age or older cannabis was well tolerated and associated with reduced pain. They started a treatment with cannabis and completed a 3-month follow-up. The study was conducted by Canopy Growth Corporation in Toronto, Canada.

The most common symptoms for which medical cannabis was authorized were pain (85.0%) and insomnia (4.8%). At baseline and at the 3-month follow-up, CBD-dominant products were authorized most frequently (54%), followed by balanced products (42%), and then THC-dominant products (4.4%). There were significant reductions in worst pain, average pain, and overall pain severity, but not pain right now or least pain. Authors wrote that “results suggest medical cannabis was safe, well-tolerated, and associated with clinically meaningful reductions in pain in this sample of older adults.”

Link: https://pubmed.ncbi.nlm.nih.gov/36131299/

29/09/2022

https://www.facebook.com/1666575596948833/posts/3272994686306908/

Introduction: Osteoarthritis (OA) is disabling and degenerative disease of the joints that is clinically characterized by pain and loss of function. With no disease-modifying treatment available, current therapies aim at pain management but are of limited efficacy. Cannabis products, specifically ca...

21/09/2022

Cannabis use in gastroparesis is associated with lower risk of vomiting

"An analysis of data from about all 50,000 patients with gastroparesis revealed, that those using cannabis had a lower risk of vomiting. Investigators of the Department of Internal Medicine Sunrise Hospital and Medical Center in Las Vegas and other hospitals from the US used a nationwide inpatient sample database from January 2012 to December 2014. The patients included in this study were the ones with primary diagnosis of gastroparesis and cannabis use.

The prevalence of cannabis use among patients hospitalized for gastroparesis was 4.2%. Cannabis use was associated with lower odds of vomiting. Patients who used cannabis were younger than non-users and more often of African American, Asian, or Pacific Islander descent. They had Medicaid insurance and a lower median household income"

Department of Internal Medicine, Sunrise Hospital and Medical Center, Las Vegas, USA.

Link: https://pubmed.ncbi.nlm.nih.gov/36067326/

16/09/2022

https://www.facebook.com/1666575596948833/posts/3267511336855243/

Background: Treatment resistance is a significant problem among young people experiencing moderate-to-severe anxiety, affecting nearly half of all patients. This study investigated the safety and efficacy of cannabidiol (CBD), a non-intoxicating component of Cannabis sativa

13/09/2022

El cannabis medicinal se refiere al uso de los compuestos bioactivos en el cannabis para tratar enfermedades. El cannabis tiene varios compuestos bioactivos que se pueden clasificar cómo cannabinoides, terpenos, …

25/08/2022

De suma importancia

The effect of cannabis on fibromyalgia may in part be explained by an improvement of mood.

"According to a study with 323 fibromyalgia patients reduction in pain by the use of cannabis was partly explained by improvement of sleep and mood. Researchers of McGill University in Montréal, Canada, conducted a 12-month prospective study. Cannabis use in all patients was initiated under the care of physicians.

Analyses indicated that reductions in patients’ levels of pain intensity were partly explained by concurrent reductions in sleep problems and negative affect. This remained significant even when accounting for patients' baseline characteristics or changes in medical cannabis directives over time"

Link: https://pubmed.ncbi.nlm.nih.gov/35876631/

23/08/2022

Información importante

CBD may reduce symptoms of chemotherapy-induced peripheral neuropathy.

"In a study with 54 patients, who underwent cancer chemotherapy with carboplatin and paclitaxel or capecitabine and oxaliplatin, CBD attenuated symptoms of chemotherapy-induced peripheral neuropathy (CIPN). Participants received either 150 mg of CBD twice-daily or a placebo for 8 days starting one day before initiation of chemotherapy. Patients were treated at the Department of Clinical Oncology and Palliative Care of Zealand University Hospital in Roskilde, Denmark.

Patients receiving CBD together with chemotherapy showed significantly lower (better) change in Z-scores in high-frequency vibrometry. The difference between CBD and placebo group was most pronounced for patients receiving carboplatin and paclitaxel. Authors concluded that “CBD attenuated early symptoms of CIPN with no major safety concerns.”

Link: https://pubmed.ncbi.nlm.nih.gov/35933415/

11/08/2022

https://www.facebook.com/1666575596948833/posts/3225850894354621/

Cholangiocarcinoma (CCA) is a rare and highly lethal disease with few effective treatment options. Cannabinoids, cannabidiol (CBD) and cannabigerol (CBG) are non-psychedelic components extracted from cannabis. These non-psychoactive compounds have shown anti-proliferative potential in other tumor mo...

08/07/2022

https://www.facebook.com/100058004925950/posts/505939398016220/

The use of cannabis is associated with a lower risk of liver cancer

"Liver cancer (hepatocellular carcinoma) is one of the most common malignancies worldwide and the fourth leading cause of cancer deaths in the world. According to a data analysis of about 101 million patients those with a diagnosis of cannabis abuse were 55% less likely to have liver cancer. The study was conducted by investigators of scientific institutions in Cleveland, Washington DC, Springfield and Phoenix.

A total of 101,231,036 patients were included in the study. Out of the total, 996,290 patients (1%) had the diagnosis of cannabis abuse versus 100,234,746 patients (99%) in the control group without cannabis abuse. Patients with cannabis use had more hepatitis B, hepatitis C, liver cirrhosis, and smoking, but had less obesity and gallstones. After adjusting for potential confounders, patients with cannabis abuse were 55% less likely to have liver cancer"

Link: https://pubmed.ncbi.nlm.nih.gov/35651376/

23/05/2022

https://www.facebook.com/100058004925950/posts/471907014752792/

Cannabis may be helpful against cancer pain according to an open study.

"In an open study with 24 cancer patients, who received capsules with traditional cannabis leaves powder, investigators observed improvements in pain and quality of life. It was conducted by the Department of Dravyaguna of GJ Patel Institute of Ayurvedic Studies and Research in New Vallabhvidyanagar of the state of Gujarat, India. Participants received the powder in a dose of 250 mg thrice daily and 50 mL of cow’s milk and 4 g of crystal sugar for 4 weeks.

There was a significant reduction in pain on the 3 tested pain scales and an improvement on a scale measuring anxiety and depression as well as an improvement in quality of life. Authors concluded that “Jalaprakshalana Shodhita Bhanga powder in a dose of 250 mg thrice per day relieves cancer induced pain, anxiety and depression significantly and does not cause any major adverse effect and withdrawal symptoms during trial period.”

Link: https://pubmed.ncbi.nlm.nih.gov/31831967/

05/05/2022

https://www.facebook.com/100058004925950/posts/458856979391129/

A cannabis extract was superior to long acting opiates in patients with neuropathic back pain

"A retrospective analysis of data from the German Pain e-Registry of adult patients, who initiated either a treatment with the cannabis extract Sativex or with long acting opiates between March 2017 and March 2020 showed that the cannabis extract “was superior to and better tolerated than add-on treatment with typical oral LAO [long acting opioids] analgesics in patients with neuropathic back pain inadequately controlled by recommended/established systemic therapies.”

The analysis was conducted by several German pain specialists.

655 patients were treated with the cannabis extract and 655 were treated with long acting opioids. The cannabis extract was associated with superior pain reduction and further symptoms, including physical function, improved more with the cannabis extract. With cannabis fewer patients experienced side effects or discontinued treatment because of side effects".

https://pubmed.ncbi.nlm.nih.gov/34480564/

23/03/2022

https://www.facebook.com/1639213479672985/posts/3094811164113202/

Resumen de la jornada "Cannabis medicinal en el control del dolor crónico. La experiencia canadiense", organizada por el Observatorio Español de Cannabis Med...

13/02/2022

Aceite de Cbd nuestras presentaciones podrás encontrarlas en la tienda Kultura Ancestral,

13/02/2022

Aceite de Cbd, Nuevas Presentaciones, informes 3111374269.

02/01/2022

https://www.facebook.com/1666575596948833/posts/3075648506041528/
Nueva información que puede ser útil.

El efecto de los extractos de cannabis en la expresión de los genes relacionados con la fibrosis.
El estudio descubrió que los extractos de cannabis con alto contenido en CBD regulan a la baja la expresión de varios genes fibróticos clave, lo que indica su potencial antifibrótico a nivel transcripcional.
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The effect of cannabis extracts on the expression of fibrosis-related genes.
Study discovered that high CBD cannabis extracts downregulate the expression of several key fibrotic genes indicating their anti-fibrotic potential at the transcriptional level.

http://opus.uleth.ca/handle/10133/6095

24/12/2021

https://www.facebook.com/100058004925950/posts/369404895003005/
Interesante información documentada

Cannabis may be helpful in endometriosis

According a retrospective electronic record-based study with 252 women by investigators of Western Sydney University and the University of Melbourne, Australia, cannabis may be helpful in the treatment of pain and other symptoms in women suffering from endometriosis. Self-rated cannabis efficacy, defined as a function of initial and final symptom ratings, was investigated across the included symptom clusters of cramps, pelvic pain, gastrointestinal pain, nausea, depression, and low libido.

Participants recorded 16193 sessions using cannabis between April 2017 and February 2020. The most common method of ingestion was inhalation (67.4%), with pain as the most common reported symptom being treated by cannabis (57.3%). Authors concluded that cannabis “appears to be effective for pelvic pain, gastrointestinal issues and mood, with effectiveness differing based on method of ingestion. The greater propensity for use of an inhaled dosage delivery may be due to the rapid onset of pain-relieving effects versus the slower onset of oral products.”

Sinclair J, Collett L, Abbott J, Pate DW, Sarris J, Armour M. Effects of cannabis ingestion on endometriosis-associated pelvic pain and related symptoms. PLoS One. 2021;16(10):e0258940.