13/05/2025
Tetracycline-class antibiotics, while effective against many bacterial infections, are strictly contraindicated during pregnancy—especially during the second and third trimesters.
Here’s why:
When taken by the mother, tetracyclines cross the placenta and bind to calcium ions in the developing fetal bones and teeth. This leads to:
➡️Permanent yellow-brown or gray tooth discoloration
➡️Enamel hypoplasia (underdeveloped enamel)
➡️Increased tooth fragility and esthetic concerns later in life
According to the FDA, tetracycline is classified under Pregnancy Category D, indicating positive evidence of human fetal risk.
Read more: https://www.drugs.com/pregnancy/tetracycline.html
