18/06/2024
99% of people are unaware that mesenchymal stem cells(MSCs) can be used to treat osteoarthritis without surgery.
Stage 1 – Minor
In stage 1 OA, patients will develop very minor wear and tear. At this stage it is unlikely you will feel any pain or discomfort.
Stage 2 – Mild
In stage 2, diagnostic images or X-rays of knee joints will show more wear and tear and bone spur growth, and though the space between the bones appears normal, people will begin to experience joint pain.
Typically, the area around the knee joint will feel stiff and uncomfortable, particularly when sitting for an extended period, after rising in the morning, or after a workout.
Stage 3 – Moderate
Stage 3 is referred to as “moderate”, where there is obvious erosion of the cartilage surfaces between bones and the gap between the bones narrows. Bone spur growth will worsen and the joint surfaces will become rough.With the progression of OA of the knee, there is obvious joint inflammation which causes more frequent pain. Stiffness will become worse and there may be popping or snapping sounds when walking.
Stage 4 – Severe
Stage 4 is considered to be severe. In stage 4 the joint space between the bones is considerably reduced, with the cartilage wearing through, leaving the joint feeling very stiff. The breakdown of cartilage leads to a chronic inflammatory response, with decreased synovial fluid causing friction, and greater discomfort moving the joint.
The advanced stage of the disease shows development of more bone spurs causing debilitating pain which makes even everyday tasks, including walking and descending stairs.