17/04/2024
โ๏ธ Today, let's raise awareness and support for those living with .
โฅ๏ธ Hemophilia, deriving from the Greek words for 'love' and 'blood', stands as the prevalent severe inherited bleeding disorder.
๐งฌ Hemophilia typically stems from genetic inheritance and results from a lack of clotting factors within the bloodstream, often linked to defects or mutations in the corresponding gene responsible for producing these factors.
๐ฅ Hemophilia A and B arise from insufficient or faulty factor VIII and factor IX proteins, leading to prolonged and excessive bleeding following minor injuries or occasionally without cause. Hemophilia C, caused by a shortage of clotting factor XI, exists but is uncommon.
๐ผ Severe hemophilia typically appears within the initial months of life, whereas mild or moderate forms may become apparent later during childhood or adolescence.
๐ธ Acquired hemophilia is an uncommon condition compared to its congenital form. It's defined by the presence of autoantibodies against Factor VIII that do not fix complement.
๐ฉบ Approximately 50% of cases of acquired hemophilia are linked to other underlying medical conditions such as pregnancy (including the postpartum period), solid tumors, autoimmune disorders (such as systemic lupus erythematosus, rheumatoid arthritis, and Sjogren's syndrome), lymphoproliferative malignancies, skin disorders, drug reactions, or even graft-versus-host disease.
๐๏ธ In instances of severe hemophilia, individuals commonly experience internal bleeding, which can affect various organs. Joint symptoms may include pain, swelling, inflammation, warmth, and limited mobility due to bleeding.
๐บ๏ธ On , let's spread knowledge, share stories, and advocate for better treatment and understanding.
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This year's event focuses on the theme "Ensuring fair access for everyone: acknowledging all bleeding disorders."
๐ The World Federation of Hemophilia envisions "Treatment for All," aiming for a global landscape where individuals with inherited bleeding disorders receive care, irrespective of the specific disorder, gender, age, or geographical location.
Together with Hemophilia Society of Malaysia, we can make a difference in the lives of those affected. ๐
References:
1.https://www.ncbi.nlm.nih.gov/books/NBK551607/
2.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626628/
