Klinik Mediviron Bukit Jelutong

08/05/2026

AT A GLANCE: What is the hantavirus and how does it spread?

Read more: https://cna.asia/4eSU2OL

28/04/2026

Why can liver damage progress silently for years before symptoms appear? 🤯

Chronic liver disease is a long term condition where the liver gradually loses its function.
Causes include infections alcohol fat buildup and metabolic disorders leading to scarring.
Over time it can result in cirrhosis and impaired detoxification and metabolism.

26/04/2026

22/04/2026

A study in a mouse model of 𝘔𝘠𝘊𝘕-amplified neuroblastoma implicates polyamine levels in affecting the makeup of the proteome and biologic characteristics of the tumor.

22/04/2026

Combined oral contraceptives and hormone-replacement therapy increase the risk of venous thromboembolism, although the absolute risk is low. Transdermal estradiol and micronized progesterone carry lower risk.

01/03/2026

Rheumatoid Arthritis Pathogenesis: Autoimmune Joint Inflammation

Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by persistent synovial inflammation and progressive joint destruction.

The pathogenesis involves activation of autoreactive T cells and B cells that target synovial tissue. Autoantibodies such as rheumatoid factor (RF) and anti–citrullinated protein antibodies (ACPAs) contribute to immune complex formation and inflammation.

Inflammatory cytokines, particularly tumor necrosis factor (TNF) and interleukin-6 (IL-6), promote synovial hyperplasia and formation of pannus tissue. This invasive pannus erodes cartilage and bone, leading to joint deformity.

Chronic inflammation also produces systemic effects beyond the joints.

Rheumatoid arthritis reflects sustained immune dysregulation resulting in destructive synovial inflammation.